Acute Disseminated Encephalomyelitis in COVID-19: presentation of two cases and review of the literature
Conclusion: A recurrent pattern of multifocal white matter lesions can occur in COVID-19 patients, possibly associated with delayed awakening. Additional studies are necessary to elucidate the role of the viral infection and of inflammatory and immune-mediated assoc iated changes in neurological manifestations of COVID-19.RESUMO Introdu ção: As manifestações neurológicas causadas pela COVID-19 ainda não estão completamente elucidadas. O comprometimento neurológico pode decorrer de um efeito viral direto em neurônios ou em células gliais, a efeito imunomediado em resposta à infecção viral, ou de um efeito secu...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

A clinical approach to hypertrophic pachymeningitis
Conclusion: HP is a manifestation of several diseases, and a precise etiological diagnosis is crucial because of the difference among treatments. An extensive investigation of patients with HP helps early diagnosis and correct treatment.RESUMO Import ância: Paquimeningite hipertrófica (PH) é uma manifestação não usual de doenças reumatológicas, infecciosas e neoplásicas. O diagnóstico etiológico por vezes é um desafio, entretanto quando realizado em tempo cria uma janela de tratamento com a possibilidade de reversão total dos sintom as. Observações: A PH é um processo inflamatório da dura-máter que pode...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Differentiation of relapsing-remitting and secondary progressive multiple sclerosis: a magnetic resonance spectroscopy study based on machine learning
Conclusions: A combined analysis of MRS and computer-aided diagnosis may be useful as a complementary imaging technique to determine MS types.RESUMO Introdu ção: A ressonância magnética é a ferramenta mais importante para o diagnóstico e acompanhamento na EM. A transição da EM recorrente-remitente (EMRR) para a EM progressiva secundária (EMPS) é clinicamente difícil e seria importante desenvolver a proposta apresentada neste estudo a fim de contribuir com o processo. Objetivo: o objetivo deste estudo foi garantir a classificação automática de grupo controle saudável, EMRR e EMPS usando a RM com espectro...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Uric acid as a marker of severity of obstructive sleep apnoea syndrome in older patients
Conclusions: No relationship was observed between uric acid level and OSAS severity, as defined by the apnoea-hypopnea index. Further studies are needed to determine the value of uric acid as a marker of OSAS, after controlling for cardiovascular comorbidities, in older patients with this syndrome.RESUMO Objetivo: o ácido úrico mostrou estar relacionado à gravidade da síndrome da apneia obstrutiva do sono (SAOS) em adultos. Avaliamos o papel do ácido úrico na SAOS em uma coorte de pacientes idosos. Métodos: Um total de 164 pacientes com idade>65 anos, admitidos em nosso laborat ório do sono entre 1º de ja...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Impulsivity prevalence in migraine patients without and with medication overuse
Conclusions: It was not possible to establish a clear connection between migraine and impulsive behavior. Association was higher among migraineurs without medication overuse.RESUMO Introdu ção: A enxaqueca é uma das condições mais comuns na prática clínica neurológica, enquadrando-se no grupo das cefaleias primárias. Sua prevalência é maior na faixa etária de 25 a 55 anos, coincidindo com o pico da produtividade econômica. Muitos pacientes recorrem ao uso abusivo de anal gésicos. O uso excessivo desses medicamentos é definido pela sua utilização por pelo menos 15 vezes ao mês, por um período de no mí...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Depression is a major determinant of sleep abnormalities in patients with epilepsy
Conclusion: We concluded that depression rather than epilepsy negatively affects sleep, suggesting that all patients should be asked about their mood and sleep complaints.RESUMO Introdu ção: O objetivo deste estudo foi identificar distúrbios do sono em pacientes com epilepsia e compará-los com uma população saudável. Também foram examinadas as características dos distúrbios do sono em pacientes com epilepsia para demonstrar o efeito e os tipos de convulsões no sono. Mé todos: O estudo consistiu em 43 pacientes com epilepsia e 53 controles saudáveis ​ ​ pareados por idade e sexo. Os dados demogr áfico...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Dementias in Brazil: increasing burden in the 2000–2016 period. Estimates from the Global Burden of Disease Study 2016
Conclusion: Population growth and aging have resulted in an increased burden of AD and other dementias in Brazil. Preventive and early diagnostic measures are essential to mitigate the burden associated with these diseases.RESUMO Introdu ção: A demência é um problema de saúde globalmente relevante, com grande carga para os pacientes e suas famílias. Este estudo teve como objetivo estimar a carga associada à doença de Alzheimer (DA) e outras demências no Brasil. Métodos: Neste estudo descritivo, foram avaliadas as estimati vas obtidas pelo estudo de Carga Global de Doença (Global Burden Disease). Descrevemos a ...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

The use of e-ASPECTS in acute stroke care: validation of method performance compared to the performance of specialists
Conclusion: e-ASPECTS is a validated and reliable tool for determining early signs of ischemia in NCCT.RESUMO Introdu ção: A avaliação rápida da tomografia de crânio sem contraste (TCSC) em pacientes com AVC de circulação anterior economiza tempo e permite um tratamento rápido e otimizado. O e-ASPECTS é um software que calcula automaticamente os valores do ASPECTS e permite uma avaliação da imagem mais precisa e ágil. Objetivo: Determinar a habilidade do e-ASPECTS em diferenciar imagens com e sem lesão. Métodos: Cento e dezesseis pacientes admitidos em uma unidade de AVC de um hospital terciário bra...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Burden of dementia in Brazil
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research

Facial palsy as a neurological complication of SARS-CoV-2
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledge of the d...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Possible acute multifocal demyelinating lesions in a COVID-19 patient
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledge of the d...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Pontine hot cross bun sign in spinocerebellar ataxia type 2
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledge of the d...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Spinal cord compression due to extramedullary hematopoiesis in beta-thalassemia
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledge of the d...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Heracles and epilepsy: the sacred disease
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledge of the d...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Intracerebral hemorrhage: update and future directions
ABSTRACT Intracerebral hemorrhage (ICH), defined as bleeding into the brain parenchyma, is a significant public health issue. Although it accounts for only 10 to 15% of strokes, it is associated with the highest morbidity and mortality rates. Despite advances in the field of stroke and neurocritical care, the principles of acute management have fundamentally remained the same over many years. The main treatment strategies include aggressive blood pressure control, early hemostasis, reversal of coagulopathies, clot evacuation through open surgical or minimally invasive surgical techniques, and the management of raised intra...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research