Editorial Board
(Source: Archives of Medical Research)
Source: Archives of Medical Research - April 1, 2018 Category: Research Source Type: research

Table of Contents
(Source: Archives of Medical Research)
Source: Archives of Medical Research - April 1, 2018 Category: Research Source Type: research

Instructions for Authors
(Source: Archives of Medical Research)
Source: Archives of Medical Research - April 1, 2018 Category: Research Source Type: research

Intranasal Administration of a Naked Plasmid Reached Brain Cells and Expressed Green Fluorescent Protein, a Candidate for Future Gene Therapy Studies
Intranasal administration (Int adm) has been well-studied and offers the possibility to deliver larger molecular weight biologics, such as proteins, viral vectors, nanoparticles, and naked plasmids to the brain and treat a variety of diseases in the central nervous system. The predominant challenge in this field is finding efficient vectors that are capable of crossing the blood-brain barrier (BBB). (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 16, 2018 Category: Research Authors: Norma Oviedo, Leticia Manuel-Apolinar, Sandra Orozco-Su árez, Teresa Juárez-Cedillo, Vilma Carolina Bekker Méndez, Emiliano Tesoro-Cruz Tags: Original Article Source Type: research

Hyperbaric-Oxygen Therapy Improves Survival and Functional Outcome of Acute Severe Intracerebral Hemorrhage-Prospective, Randomized Controlled Trial
Prognosis of spontaneous intracerebral hemorrhage (ICH) remains poor worldwide. (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 13, 2018 Category: Research Authors: Xiaowei Li, Jingze Li, Xuehui Yang, Zhaosheng Sun, Jinrong Zhang, Wangmiao Zhao, Shuzhi Dong, Cong Li, Yanqiao Ye, Jianchao Chen, Yongqian Li, Yi Xiang, Jianhui Mao, Guangjie Li, Hong Guo, Wenchao Zhang, Hao Guo, Yazhao Zhang, Mingzhe Zhang, Wanzeng Zhang Tags: Original Article Source Type: research

Inhibitory Effect of Artesunate on Growth and Apoptosis of Gastric Cancer Cells
The present study aimed to explore the inhibitory effect of artesunate on the growth and apoptosis of gastric cancer cells, in order to search for high effective and low toxic anti-gastric cancer drugs. (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 12, 2018 Category: Research Authors: Lei Wang, Liang Liu, Jing Wang, YueTong Chen Tags: Original Article Source Type: research

Spinogenesis and Plastic Changes in the Dendritic Spines of Spinal Cord Motoneurons After Traumatic Injury in Rats
Spinal cord injury (SCI) is highly incapacitating, and the neurobiological factors involved in an eventual functional recovery remain uncertain. Plastic changes to dendritic spines are closely related with the functional modifications of behavior. (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 10, 2018 Category: Research Authors: Eliseo Portilla-de Buen, Hermelinda Salgado-Ceballos, David Gonz ález-Tapia, Caridad Leal-Cortés, Rodrigo Mondragón-Lozano, Stephanie Sánchez-Torres, Laura Álvarez-Mejía, Omar Fabela-Sánchez, Néstor I. Martínez-Torres, Myrna M. González-Ramírez Tags: Original Article Source Type: research

Koch Postulate: Why Should we Grow Bacteria?
Understanding infectious diseases has long relied on the Koch postulate, which consists of the pure culture of microorganisms. The advent of molecular methods in clinical microbiology has led the phasing out of culture as a diagnostic tool and metagenomics has become the technique most commonly used to assess the impact of commensal microbes on human health. However, culturing microbes has led to substantial advances, even recently, in infectious diseases involving fastidious microorganisms, as evidenced by the Tropheryma whipplei or Bartonella species. (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 6, 2018 Category: Research Authors: Jean-Christophe Lagier, Gr égory Dubourg, Sophie Amrane, Didier Raoult Tags: Review Article Source Type: research

Koch Postulate: Why do we Should Grow Bacteria?
Understanding infectious diseases has long relied on the Koch postulate, which consists of the pure culture of microorganisms. The advent of molecular methods in clinical microbiology has led the phasing out of culture as a diagnostic tool and metagenomics has become the technique most commonly used to assess the impact of commensal microbes on human health. However, culturing microbes has led to substantial advances, even recently, in infectious diseases involving fastidious microorganisms, as evidenced by the Tropheryma whipplei or Bartonella species. (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 6, 2018 Category: Research Authors: Jean-Christophe Lagier, Gr égory Dubourg, Sophie Amrane, Didier Raoult Tags: Review Article Source Type: research

Association Between the Brain-derived Neurotrophic Factor Val66Met Polymorphism and Overweight/Obesity in Pediatric Population
The brain-derived neurotrophic factor (BDNF) rs6265 (G196A; Val66Met) single nucleotide polymorphism has been associated with BMI and obesity in distinct populations, both adult and pediatric, with contradictory results involving either Val or Met as the risk variant. (Source: Archives of Medical Research)
Source: Archives of Medical Research - March 2, 2018 Category: Research Authors: Jos é Darío Martínez-Ezquerro, Mario Enrique Rendón-Macías, Gerardo Zamora-Mendoza, Jacobo Serrano-Meneses, Beatriz Rosales-Rodríguez, Deyanira Escalante-Bautista, Maricela Rodríguez-Cruz, Raúl Sánchez-González, Yessica Arellano-Pineda, Mardia L Tags: Original Article Source Type: research

Interaction Between Depression, Obesity, and Type 2 Diabetes: A Complex Picture
Depression plays an important role in the pathogenesis and treatment of obesity and type 2 diabetes (T2D). However, its relevance is frequently unrecognized by clinicians and researchers. The purpose of this review is to present a critical analysis of the evidence linking depression and metabolic disorders and to highlight the practical implications of this complex relationship. Evidence obtained from epidemiological, basic, clinical and controlled studies demonstrate that the association goes beyond a random phenomenon. (Source: Archives of Medical Research)
Source: Archives of Medical Research - February 22, 2018 Category: Research Authors: Magdalena del Roc ío Sevilla-González, Brenda Macale Quintana-Mendoza, Carlos Alberto Aguilar-Salinas Tags: Review Article Source Type: research

Hypolipidemic Components from Medicine Food Homology Species Used in China: Pharmacological and Health Effects
Hyperlipidemia is a systemic disease caused by abnormal human lipid metabolism. Dietary control and treatment on hyperlipidemia is now a popular therapy pathway. This paper focuses on the medicine food homology (MFH) species used in China with hypolipidemic function, and emphasizes on the active ingredients and their pharmacological effect. The single herbal and its hypolipidemic active ingredients are summarized through reviewing the relevant literatures published in the past twenty years. The ingredients are divided into polysaccharides, flavonoids, steroidal saponins, quinones, alkaloids and others, of which the related...
Source: Archives of Medical Research - February 13, 2018 Category: Research Authors: De-xing Song, Jian-guo Jiang Tags: Review Article Source Type: research

Hearing Loss in Type 2 Diabetes in Association with Diabetic Neuropathy
Reports assessing hearing abnormalities in diabetes are debated. We aimed to evaluated auditory alterations and their possible associations with vascular and neurological dysfunction in 160 Type 2 diabetes mellitus individuals and 100 age and sex-matched healthy controls. (Source: Archives of Medical Research)
Source: Archives of Medical Research - February 9, 2018 Category: Research Authors: Huihui Ren, Zhenggang Wang, Zhongyao Mao, Ping Zhang, Chunfang Wang, Aiguo Liu, Gang Yuan Tags: Original Article Source Type: research

Expanding our Understanding of the Role of the Microbiome in Health and Disease
Our understanding of the microbial side of ourselves, and its implications in health and disease, has been completely transformed in the past decade. Advances in DNA sequencing, and in the computational techniques required to understand this wealth of DNA sequences, allow us to read out the complex microbial communities that inhabit our bodies and our world at unprecedented rates. However, relating this information to function, and learning how to  modify our microbiomes to improve health, remain important challenges in the field. (Source: Archives of Medical Research)
Source: Archives of Medical Research - February 8, 2018 Category: Research Authors: Rob Knight Tags: Preface Source Type: research