Association Between miR-149 Gene rs2292832 Polymorphism and Risk of Gastric Cancer
Accumulating evidence suggested that microRNA (miRNA) genes take part in different processes associated with gastric cancer (GC). The single nucleotide polymorphisms (SNPs) located on miRNA sequences may affect the interaction with their target mRNAs and consequently the genetic susceptibility to GC. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 28, 2018 Category: Research Authors: Lili Zhang, Qingna Liu, Fan Wang Tags: Original Article Source Type: research
Effect of Fat Graft ıng on Postoperatıve Intraabdomınal Adhesions on a Rat Model
We aimed to evaluate the effect of fat grafting on postoperative intraabdominal adhesions by promoting mesothelial healing on a rat model. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 28, 2018 Category: Research Authors: Asudan Tugce Bozkurter Cil, Ilhami Oguzhan Aydogdu Tags: Original Article Source Type: research
Association Between miR-149 Gene rs2292832 Polymorphism and Risk of Gastric Cancer: A Case-control Study
Accumulating evidence suggested that microRNA (miRNA) genes take part in different processes associated with gastric cancer (GC). The single nucleotide polymorphisms (SNPs) located on miRNA sequences may affect the interaction with their target mRNAs and consequently the genetic susceptibility to GC. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 28, 2018 Category: Research Authors: Lili Zhang, Qingna Liu, Fan Wang Tags: Original Article Source Type: research
Role of Reduced Nitric Oxide in Liver Cell Apoptosis Inhibition During Liver Damage
Hepatic injury is a major event in liver surgery and may lead to liver cell apoptosis. Nitric oxide (NO) is an unstable, carbon-centered radical with a short half-time and a key role in molecular signaling. Increasing evidence demonstrates that NO plays an important role in the liver cell apoptosis caused by hepatic ischemia reperfusion (IR) injury and other liver damage. Our recent article summarized the association between elevated nitric oxide levels and hepatic cell apoptosis during liver injury. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 27, 2018 Category: Research Authors: Ying-yi Wang, Meng-ting Chen, Hui-min Hong, Ying Wang, Qian Li, Hui Liu, Mei-wen Yang, Fen-fang Hong, Shu-long Yang Tags: Review Article Source Type: research
Chikungunya in Bolivia: Still a Neglected Disease?
We read with great interest the article by Murillo-Zamora et al about chikungunya (CHIKV) (1), an emerging condition in the Americas, but still neglected in some countries. Then, we would like to take the opportunity to highlight the current situation of this disease in Bolivia, as well as difficulties and gaps of knowledge for its diagnosis, treatment and control. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 27, 2018 Category: Research Authors: Juan Pablo Escalera-Antezana, David R. Murillo-Garc ía, Alfonso J. Rodriguez-Morales Tags: Letter to the Editor Source Type: research
Roles of Reduced Nitric Oxide in Liver Cell Apoptosis Inhibition During Liver Damage
Hepatic injury is a major event in liver surgery and may lead to liver cell apoptosis. Nitric oxide (NO) is an unstable, carbon-centered radical with a short half-time and a key role in molecular signaling. Increasing evidence demonstrates that NO plays an important role in the liver cell apoptosis caused by hepatic ischemia reperfusion (IR) injury and other liver damage. Our recent article summarized the association between elevated nitric oxide levels and hepatic cell apoptosis during liver injury. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 27, 2018 Category: Research Authors: Ying-yi Wang, Meng-ting Chen, Hui-min Hong, Ying Wang, Qian Li, Hui Liu, Mei-wen Yang, Fen-fang Hong, Shu-long Yang Tags: Review Article Source Type: research
Promoter Polymorphisms of TNF- α Gene as a Risk Factor for Schizophrenia
The latest data showed a link between mental disorders and altered immune function. Schizophrenia is a multifactorial disease with numerous changes in the immunological system. The TNF- α gene is a strong candidate for schizophrenia susceptibility. The focus of this paper were the −1031 T/C, −863 C/A, −857 C/T, −308 G/A single nucleotide polymorphisms (SNPs) of the TNF-α gene. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 26, 2018 Category: Research Authors: Renata Suchanek-Raif, Pawe ł Raif, Małgorzata Kowalczyk, Monika Paul-Samojedny, Krzysztof Kucia, Wojciech Merk, Jan Kowalski Tags: Original Article Source Type: research
Decompensated Chronic Heart Failure Reduces Plasma L-carnitine
The heart has an intense aerobic metabolism and is among the most metabolically active organs in the body. Its tissue stores fatty acid, the main energetic substrate, and requires high concentrations of plasma L-carnitine. This nutrient is essential in the transport of fatty acids to the mitochondria to generate energy and maintain the proper concentration of coenzyme A free. In decompensated chronic heart failure metabolic changes, associated with inflammation, alter the metabolism of L-carnitine and compromise cardiac energy metabolism. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 26, 2018 Category: Research Authors: Sheila Moreira da Silva Guimar ães, Wanise Maria de Souza Cruz, Guilherme de Souza Weigert, Fernanda Bertão Scalco, Alexandre Siciliano Colafranceschi, Marcia Gonçalves Ribeiro, Gilson Teles Boaventura Tags: Preliminary Report Source Type: research
A Novel Magnetic Nanoparticle for Early Detection of Amyloid Plaques in Alzheimer's Disease
Early diagnosis of Alzheimer's disease (AD) remains challenging even with the assistance of imaging. Radiation exposure limits the application of positron emission tomography (PET) for amyloid imaging. Magnetic resonance imaging (MRI) offers superior spatial resolution without the disadvantage of radiation exposure. We developed Mn0.6Zn0.4Fe2O4 (MZF) modified by Pittsburgh compound B (PiB) to specifically bind to amyloid plaques. Coated with amphiphilic nanopolymer 6sPCL-b-P(MEO2MA-co-OEGMA), PiB-MZF was stable, biocompatible, and approximately 100 nm in size. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 26, 2018 Category: Research Authors: Jiaqi Zeng, Jiaqi Wu, Minghua Li, Peijun Wang Tags: Preliminary Report Source Type: research
Promoter Polymorphisms of TNF- α Gene (−1031 T/C, −863 C/A, −857 C/T, −308 G/A) as a Risk Factor for Schizophrenia
The latest data showed a link between mental disorders and altered immune function. Schizophrenia is a multifactorial disease with numerous changes in the immunological system. The TNF- α gene is a strong candidate for schizophrenia susceptibility. The focus of this paper were the −1031 T/C, −863 C/A, −857 C/T, −308 G/A single nucleotide polymorphisms (SNPs) of the TNF-α gene. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 26, 2018 Category: Research Authors: Renata Suchanek-Raif, Pawe ł Raif, Małgorzata Kowalczyk, Monika Paul-Samojedny, Krzysztof Kucia, Wojciech Merk, Jan Kowalski Tags: Original Article Source Type: research
Discriminatory Accuracy of Preeclampsia Risk Factors in Primary Care
Although it is common to use risk factors in the screening for preeclampsia, they do not always accurately identify patients who truly have this condition. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 25, 2018 Category: Research Authors: Hid Felizardo Cordero-Franco, Ana Mar ía Salinas-Martínez, Tania Abigail García-Alvarez, Eloísa Verónica Maldonado-Sánchez, Francisco Javier Guzmán-de la Garza, Alvaro Mathiew-Quirós Tags: Original Article Source Type: research
Discriminatory Accuracy of Preeclampsia Risk Factors in a Primary Care
Although it is common to use risk factors in the screening for preeclampsia, they do not always accurately identify patients who truly have this condition. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 25, 2018 Category: Research Authors: Hid Felizardo Cordero-Franco, Ana Mar ía Salinas-Martínez, Tania Abigail García-Alvarez, Eloísa Verónica Maldonado-Sánchez, Francisco Javier Guzmán-de la Garza, Alvaro Mathiew-Quirós Tags: Original Article Source Type: research
Apolipoprotein E in Cardiovascular Diseases: Novel Aspects of an Old-fashioned Enigma
The presence of different APOE isoforms represents a well-known risk factor for cardiovascular diseases. Besides the pleiotropic effects of APOE polymorphism on heart and neurological diseases, this review summarizes the less-known functions of APOE and the possible implications for cardiovascular disorders. Beyond the role as lipid transporting protein, its involvement in lipid membrane homeostasis and signaling, as well as its nuclear transcriptional effects suggests a more complex role of APOE, receiving great interest from researchers and physicians from all medical fields. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 10, 2018 Category: Research Authors: Elisa A. Liehn, Victor Ponomariov, Rodica Diaconu, Ioana Streata, Mihai Ioana, Gustavo E. Crespo-Avilan, Sauri Hern ández-Reséndiz, Hector A. Cabrera-Fuentes Tags: Review Article Source Type: research
Vaccination Status and Other Preventive Measures in Medical Schools. Big Needs and Opportunities
Proper immunization and knowledge in infection prevention are key factors in protecting medical students. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 5, 2018 Category: Research Authors: Diana Vilar-Compte, Daniel de-la-Rosa-Martinez, Samuel Ponce de Le ón Tags: Original Article Source Type: research
Vaccination Status and Other Preventive Measures in Medical School. Big Needs and Opportunities
Proper immunization and knowledge in infection prevention are key factors in protecting medical students. (Source: Archives of Medical Research)
Source: Archives of Medical Research - September 5, 2018 Category: Research Authors: Diana Vilar-Compte, Daniel de-la-Rosa-Martinez, Samuel Ponce de Le ón Tags: Original Article Source Type: research
