Association between body mass index and dental caries among special care female children in Makkah City
CONCLUSION:This study demonstrated a significant association between caries frequency and overweight/obesity in special care school children.  LIMITATIONS:Since the data was cross-sectional, causal relationships cannot be established and the observed association could be due to other unexplored factors. Because of cultural and ethical consideration, including segregation of gender in Saudi Arabia, only female children were included in the present study, which limited the findings.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 31, 2017 Category: General Medicine Tags: ISSUE 1 Source Type: research

The association between body mass index and frequency of emergency department visits and hospitalization for asthma exacerbation in a pediatric population
CONCLUSION: There was no evidence of an association between BMI and frequency of ED visits and hospitalization for asthma exacerbation among children.  LIMITATIONS: This study included patients as young as 2 years, while asthma is only well-defined in children>5 years. Asthma triggers that can cause exacerbation despite body weight were not included. We included only frequency of ED visits and hospitalization, which may be inadequate to measure asthma severity.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Admission of term infants to the neonatal intensive care unit in a Saudi tertiary teaching hospital: cumulative incidence and risk factors
CONCLUSION: A growing number of term infants are admitted unexpectedly to the NICU. The risk factors and pattern of admission of term infants to the NICU should receive more attention in quality improvement and management agendas. LIMITATIONS: This was a single-center study with limited access to information about unbooked mothers and details of the hospital stay of the admitted neonates.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Q192R polymorphism in the PON1 gene and familial hypercholesterolemia in a Saudi population
CONCLUSION: In conclusion, the Q192R polymorphism in the PON1 gene is associated with FH in the Saudi population. Our results confirmed that the R allele, QR, and dominant model genotypes were associated with FH. LIMITATION: Only a single variant (Q192R) was analyzed, and the medical and family histories of the patients were not known.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Cost-effectiveness of oral agents in relapsing-remitting multiple sclerosis compared to interferon-based therapy in Saudi Arabia
CONCLUSION: None of the DMDs were found to be cost-effective in the treatment of RRMS at a WTP threshold of $100000 in this analysis. The DMDs would only be cost-effective at a WTP above $300000.  LIMITATIONS: The current analysis did not reflect the Saudi population preference in valuation of health states and did not consider the societal perspective in terms of cost.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Influence of body mass index on severity of dental caries: cross-sectional study in healthy adults
CONCLUSION: Dental caries was not associated with BMI but age significantly influenced the DMFT index and gender was associated with more missing teeth. Further longitudinal studies with larger cohorts from several geographic regions are warranted. LIMITATION:Convenience sampling and recruitment from a single dental center may have some impact on the generalization of data.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Prognostic factors for epilepsy following first febrile seizure in Saudi children
CONCLUSION: The rate of epilepsy following first febrile seizure in Saudi children is within the range of values reported in different populations. Although most childhood febrile seizures are self-limiting, careful observation is needed, particularly for children who exhibit factors associated with epilepsy.  LIMITATIONS:Conducted at a single center in Saudi Arabia, which may limit generalizability.   (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Retrospective review of pediatric status epilepticus in 116 Saudi patients: predictors of outcome
CONCLUSION: Pediatric status epilepticus is highly associated with neurological morbidity. The main pre.dictor of outcome is underlying symptomatic etiology of SE and to a lesser degree the presence of a history of epilepsy. Duration does not seem to play a major role.  LIMITATIONS:The main limitation is the retrospective chart review nature of the study with possible bias.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Prevalence and predictors of myocardial ischemia by preoperative myocardial perfusion single photon emission computedtomography in patients undergoing noncardiac surgery
CONCLUSIONS: Because of the low positive predictive value of myocardial perfusion SPECT, utilization of the technique in the workup of cardiac patients undergoing noncardiac surgery has been inappropriate. Myocardial perfusion SPECT should be restricted to only clearly defined appropriate use criteria.  LIMITATIONS: Relatively small number of patients and retrospective design.    (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Recurrence of malignant melanoma presenting as black-colored pyopneumothorax: a rare entity
We report a 63-year-old patient with black-colored pus (pyopneumothorax) resulting from an infected pleural effusion associated with metastatic malignant melanoma of the skin. The patient was also positive for Pseudomonas, so the color was unexpected. Although rare, malignant melanoma can present as a black pleural effusion due to the presence of melanocytes in the pleural fluid. Black pleural fluid should raise the suspicion of malignant melanoma.  SIMILAR CASES PUBLISHED:Nine cases of black pleural effusion due to different causes have been reported.1,2 Three cases of black pleural effusion due to metastat...
Source: Annals of Saudi Medicine - December 11, 2017 Category: General Medicine Tags: ISSUE 6 Source Type: research

Reply
  Dear Dr. Shaker: We thank Dr Shakers comments on our article " Osteoporosis among male Saudi Arabs: A pilot study. Annals Saudi Med 2006; 26(6):450-54.1 The (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 22, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Antioxidant Defense and Oxidative Stress in Children with Acute Hepatitis A
CONCLUSIONS: Our findings show that pediatric patients with acute hepatitis A were influenced by oxidative stress, resulting in significantly lower levels of plasma antioxidants and increased lipid peroxidation. In the absence of other therapeutic options, antioxidant vitamin supplements could be added to the therapy for these patients to help reestablish the oxidant status balance. Further investigations to confirm this suggestion are recommended. Ann Saudi Med 2011; 31(3): 258-262PMID: 21623054 DOI: 10.4103/0256-4947.81538 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research

Sexually Transmitted Infections in Pakistan
BACKGROUND AND OBJECTIVES: Sexually transmitted infections (STIs) represent a major global health problem leading to morbidity, mortality and stigma. Prior to this study there was no information on the prevalence and knowledge of STIs in Faisalabad, Pakistan. DESIGN AND SETTING: Prospective, cross-sectional study in patients attending STI clinics from July 2006 to September 2009. PATIENTS AND METHODS: After obtaining consent, patients completed structured questionnaires used for behavioral surveys. Blood and urethral swabs were collected and tested for syphilis, gonococcus, genital herpes, chlamydia and chancroid...
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research