Desmoplastic melanoma: a rare variant with challenging diagnosis
Abstract: Desmoplastic melanoma, a distinct and uncommon variant, is characterized as an invasive lesion with proliferation of fusiform melanocytes in the dermis and subcutaneous tissue, associated with varying patterns of desmoplasia. Neurotropism and neural differentiation may occur. The clinical presentation is variable and nonspecific, easily confused with other fibrous neoplasms. The disease is locally aggressive and shows lower metastasis rates than other types of melanoma. Histopathology may be insufficient, requiring positive immunohistochemistry for S-100 protein and other antigens of melanocytic differentiation. ...
Source: Anais Brasileiros de Dermatologia - February 4, 2019 Category: Dermatology Source Type: research
S100 negative granular cell tumor of the oral cavity: dermoscopy and surgical approach
We report the case of a 47-year-old male patient with S100 negative granular cell tumor of the oral cavity, focusing on dermoscopic features as well as surgical approach, not previously reported in the literature. The study contributes to the literature on dermoscopy and surgical treatment for this tumor and provides a practical approach to differentiating non-neural granular cell tumors and granular cell tumors. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - February 4, 2019 Category: Dermatology Source Type: research
Follicular thyroid carcinoma metastatic to skin: a small papule and a big diagnostic change
We report a case of cutaneous metastasis in a patient with follicular thyroid carcinoma and breast carcinoma. Because of the association of these two neoplasms, the possibility of Cowden Syndrome - multiple hamartoma syndrome - was raised, but was excluded by genetic analysis of PTEN gene. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - February 4, 2019 Category: Dermatology Source Type: research
Adult female acne: a guide to clinical practice
Conclusion: Different from teenage acne, adult female acne presents some characteristics and multiple etiopathogenic factors that make its management more complex. This guide provides recommendations for best clinical practices and therapeutic decisions. However, the authors consider that additional studies are needed in order to provide more evidence for adult female acne to be better understood. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - February 4, 2019 Category: Dermatology Source Type: research
Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection
Conclusions: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - February 4, 2019 Category: Dermatology Source Type: research
