Outcome in dogs diagnosed with splenic hematomas
Differential diagnoses for a canine splenic mass include malignant tumors as well is benign masses including splenic hematoma and lymphoid hyperplasia. One study led to the development of the so-called two-thirds rule: approximately two-thirds of splenic masses will be malignant and two-thirds of those will be hemangiosarcomas (HSAs), the remaining one third of splenic masses would be expected to be benign. The most common benign splenic lesion reported in the dog is splenic hematoma. Canine splenic hematoma and HSA can have a similar clinical presentation and gross appearance at the time of surgery. (Source: Advances in S...
Source: Advances in Small Animal Medicine and Surgery - February 28, 2017 Category: Veterinary Research Tags: Oncology Source Type: research

Comparison of surgically treated large versus small intestinal volvulus
Intestinal volvulus is the pathologic twisting of a section of bowel around its mesenteric attachment site. Small and large intestinal volvulus is most common in horses, cattle, swine, and humans. The condition occurs uncommonly in dogs and cats, with small intestinal volvulus occurring more commonly than large intestinal volvulus. Intestinal volvulus is a life-threatening condition which warrants medical stabilization and surgical intervention. This pathologic condition results in luminal obstruction and vascular compromise, leading to ischemia, necrosis of the affected bowel segment, and subsequent circulatory shock. (So...
Source: Advances in Small Animal Medicine and Surgery - February 28, 2017 Category: Veterinary Research Tags: Surgery (Soft Tissue) Source Type: research

Beyond Three Circles: A Broader View of One Health
One Health has emerged as a constructive framework to address numerous global issues at the animal, human, and environment interface. The concept that there is a link between human health and the environment and animal health is not new and can be traced as far back as to the Greek physician Hippocrates (c. 460 BCE to c. 370 BCE) in his text On Airs, Waters, and Place where he promoted the concept that public health depended on a clean environment. Lucius Junis Moderatus Columella wrote a work Segregation and Quarantine, which was an early text on agriculture and led to a basic form of One Health in that it advised people ...
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Authors: Gary Vroegindewey Tags: Guest Editorial Source Type: research

Tooth brushing inhibits oral bacteria
The incidence of periodontal diseases increases in dogs when they become older, and approximately 80% of dogs have some stage of periodontal disease. The most common procedure to treat periodontal diseases in dogs is scaling, which should be performed under general anesthesia. Owing to the risks of anesthesia, it may be difficult to obtain consent from the owners. Even if consent is obtained, the only treatment option for dogs with severe periodontal disease is tooth extraction. Therefore, prevention is more important than treatment in case of periodontal disease. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Dentistry Source Type: research

Comparison between clinical dermatophyte test medium and laboratory culture for dermatophytosis
Dermatophytoses are among the most frequent skin diseases of pets and livestock. A wide variety of dermatophyte species have been isolated from animals. The zoophilic species responsible for the majority of cases are Microsporum canis, Trichophyton mentagrophytes complex, Trichophyton equinum, and Trichophyton verrucosum, as well as the geophilic species Microsporum gypseum. In dogs and cats, the differential diagnosis is extensive as a consequence of the variable clinical appearance of infection. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Dermatology Source Type: research

Serum concentrations of SDMA and creatinine
Chronic kidney disease (CKD) is a common cause of morbidity and mortality in dogs. Antemortem prevalence of CKD varies from 0.9% in dogs of all ages examined to 2.4% in dogs between 10 and 15 years of age. Regardless of the initiating cause, CKD tends to be progressive. Progression occurs because of persistence of primary disease or addition of other renal insults or complications. Once glomerular filtration rate (GFR) has decreased to 30 to 50% of normal, progression to end-stage renal failure tends to be inevitable. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Nephrology/Urology Source Type: research

Management of spinal epidural empyema
Spinal epidural empyema and spinal abscess formation refer to bacterial infections within the extradural space. Although an abscess is enclosed by inflammatory tissue, the limits for spinal empyema are the epidural space itself. These rare conditions have the potential to cause severe myelopathy in dogs. The term “abscess” is most commonly used in human medicine, whereas the term “empyema” has been used more commonly in companion animals and is often used to describe both conditions. Differentiating between an abscess and empyema may be difficult without histologic confirmation. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Neurology Source Type: research

Hypersensitivity reactions to L-asparaginase in dogs and cats
The tumor inhibitory properties of L-asparaginase were discovered in the 1960s. L-asparaginase hydrolyzes asparagine to aspartic acid leading to decreased systemic L-asparagine levels. This, coupled with a limited asparagine synthetase activity in malignant lymphoid cells, decreases protein synthesis leading to cellular death. Toxicities related to L-asparaginase fall into two categories: those related to hypersensitivity to the foreign protein and those related to decreased asparagine and protein synthesis inhibition. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Oncology Source Type: research

AOVET: Masters course on advanced osteotomy – small animal
Orlando, Florida (Sept 8 –10, 2016) (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Surgery (Orthopedics) Source Type: research

Comparison of tensile strength among several suture patterns for incision closure
Many suture patterns and materials have been described for routine incision closure. Considerations for selection of an appropriate suture pattern and material include inflammatory response, risk of surgical site infection, knot security, tensile strength, suture handling, cost, risk of dehiscence, and speed of application. Each suture pattern has its unique advantages and disadvantages. Selection of suture patterns for routine skin closure is based primarily on surgeon preference rather than scientific evidence or surgical principles to minimize risks of infection and foreign material and reduce tension. (Source: Advances...
Source: Advances in Small Animal Medicine and Surgery - January 31, 2017 Category: Veterinary Research Tags: Surgery (Soft Tissue) Source Type: research

Feline Lower Urinary Tract Disease – Should We Prescribe Antibiotics?
Signs of lower urinary tract disease (LUTD) are one of the most common presenting complaints in feline medicine. Over time, our thinking about LUTD in cats has undergone some paradigm shifts. Even the name has changed – many of us remember the days of “feline urologic syndrome.” Today, about two-thirds of cats with LUTD signs are diagnosed with idiopathic cystitis; the second and third most common diagnoses are uroliths and behavior problems, respectively. Therefore, part of our first-line treatment approac h to most patients should involve analgesic therapy with environmental assessments and measures to reduce stres...
Source: Advances in Small Animal Medicine and Surgery - December 31, 2016 Category: Veterinary Research Authors: Susan Little Tags: Guest Editorial Source Type: research

Behavioral response and cost comparison of manual versus pharmacologic restraint in dogs
Chemical restraint is widely used in veterinary medicine for outpatient procedures which are among the most common types of procedures in veterinary primary care. Veterinarians may differ on when they choose to sedate or ask the veterinary health care team to manually restrain the patient. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 31, 2016 Category: Veterinary Research Tags: Behavior Source Type: research

Evaluation of gel tube agglutination crossmatch in dogs
Prior to transfusion, the blood compatibility of the recipient with the donor blood product must be assured. Pretransfusion testing typically involves blood typing and cross-match tests. Traditionally, cross-match tests have been performed by veterinary diagnostic laboratories, as the standard tube method requires expertise, is tedious to perform, and interpretation of the results is somewhat subjective. A major cross-match gel tube agglutination test is available as a point-of-care test for dogs and cats. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 31, 2016 Category: Veterinary Research Tags: Clinical Pathology Source Type: research

Prevalence and clinicopathologic features of triaditis in cats
The term triaditis has been coined to describe concurrent inflammatory bowel disease (IBD), the biliary system, and the pancreas in cats. However, the terminology for this condition remains controversial. The controversy over the characterization of triaditis as a separate syndrome is not surprising, considering that the 3 component diseases remain poorly characterized with regard to their pathogenesis and their clinical, laboratory, and histopathological manifestations. In addition, the inconsistent clinical and laboratory findings and lack of specific and sensitive laboratory tests often make their ante-mortem diagnosis ...
Source: Advances in Small Animal Medicine and Surgery - December 31, 2016 Category: Veterinary Research Tags: Gastroenterology Source Type: research

Correlation of urine and serum biomarkers with renal damage and survival in dogs
Chronic kidney disease (CKD) is a common cause of morbidity and mortality in dogs, and current noninvasive methods of diagnosis often lack sensitivity, specificity, or both for early disease detection and for identification of the underlying disease process. Clinically, CKD in dogs is typically detected by the presence of renal azotemia, persistent renal proteinuria, or both, often in conjunction with decreased urine concentrating ability, abnormal findings on urine sediment examination, and abnormal appearance of the kidneys on ultrasound. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 31, 2016 Category: Veterinary Research Tags: Neurology/Urology Source Type: research