Masthead
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Editorial Board
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Table of Contents
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Hemodialysis Catheter Device Protection: Damned if We Do; Patients Are Damned if We Don't
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Daniel L. Landry, Gregory L. Braden, Jerry Yee (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

The Many Faces of Infection in CKD: Evolving Paradigms, Insights, and Novel Therapies
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Mohanram Narayanan (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Immune Dysfunction and Risk of Infection in Chronic Kidney Disease
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Maaz Syed-Ahmed, Mohanram NarayananCardiovascular disease and infections are directly or indirectly associated with an altered immune response, which leads to a high incidence of morbidity and mortality, and together, they account for up to 70% of all deaths among patients with chronic kidney dysfunction. Impairment of the normal reaction of the innate and adaptive immune systems in chronic kidney disease predisposes patients to an increased risk of infections, virus-associated cancers, and a diminished vaccine response. ...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Current Concepts in Hemodialysis Vascular Access Infections
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Lalathaksha Kumbar, Jerry YeeInfection-related causes are second only to cardiovascular events for mortality among end-stage renal disease patients. This review will provide an overview of hemodialysis catheter-, graft-, and fistula-related infections with emphasis on diagnosis and management in specific settings. Use of catheters at the initiation of dialysis has remained unchanged at 80%. Of all access-related bloodstream infections (BSIs), 70% occur in patients with catheters. The risk factors for BSIs in tunneled, cuf...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Peritoneal Dialysis Access Associated Infections
This article reviews current knowledge with regards to prevention of PD-associated infections, and the diagnosis and management of exit site infections and peritonitis. (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Clostridioides difficile Infection in Chronic Kidney Disease/End-Stage Renal Disease
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Mayur S. Ramesh, Jerry YeeClostridioides difficile infection (CDI) is a major health-care burden and increasingly seen in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Increased antibiotic use, alteration in host defenses, and gastric acid suppression are some of the etiologies for increased risk of CDI in these populations. Patients with CKD/ESRD have a higher risk of initial episode, recurrence, and development of severe CDI than those without CKD or ESRD. Diagnosis and management of CDI...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Mycobacterial Infections in Patients With Chronic Kidney Disease and Kidney Transplantation
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Lizbeth J. Cahuayme-Zuniga, Karen B. BrustPatients with chronic kidney disease have impaired immunity that increases their risk of infection. Increased incidence of mycobacterial infections, in particular Mycobacterium tuberculosis, is described in patients undergoing hemodialysis and peritoneal dialysis as well as after kidney transplantation in low-prevalence and high-prevalence settings. Diagnosis of this infection can be challenging because of atypical presentations that may lead to treatment delay and, consequently, ...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Pathophysiology and Treatment of Hepatitis B and C Infections in Patients With End-Stage Renal Disease
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Vivek Soi, Chantale Daifi, Jerry Yee, Elizabeth AdamsAn in-depth understanding of viral hepatitis is important to the care of patients with end-stage renal disease undergoing hemodialysis. Both hepatitis B and C viruses are acquired through hematogenous spread and can lead to horizontal transmission. Concurrent hepatic and renal injuries have ominous outcomes with significant morbidity. Hepatitis B incidence has decreased through practices including vaccination of nonimmune individuals and isolation of patients with the d...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Prevention and Treatment of Multidrug-Resistant Organisms in End-Stage Renal Disease
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): John K. Midturi, Sangeetha RanganathChronic kidney disease patients are at high risk for infections because of multidrug-resistant organisms. Infections are the second most common cause of death in patients with ESRD. Patients with ESRD are prone to infections given alterations in immunity, increased rates of colonization with multidrug-resistant organisms, increased hospitalizations, and interactions with health care systems. Infections range from urinary tract infections, pneumonia, skin and soft tissue infections, cent...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Antibiotic Dosing in Chronic Kidney Disease and End-Stage Renal Disease: A Focus on Contemporary Challenges
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): A. Mary VilayInfections are an important cause of morbidity and mortality among patients with chronic kidney disease. Therefore, appropriate antibiotic dosing is imperative to achieve positive patient outcomes while minimizing antibiotic dose-related toxicity. Accurately assessing renal function and determining the influence of renal replacement therapy on antibiotic clearance makes drug dosing in this patient population challenging. Furthermore, as technological advances in hemodialysis and peritoneal dialysis occur, res...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Vaccination in Chronic Kidney Disease
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): Snigdha Reddy, Chandrika Chitturi, Jerry YeeInfections after cardiovascular disease are the second most common cause of death in the chronic kidney disease population. Vaccination is an important component of maintaining health and wellness in patients with kidney disease. There is a changing epidemiologic landscape for several vaccine-preventable illnesses from childhood to adulthood and unfounded public perception of safety concerns. Several mechanisms have been proposed to cause inadequate vaccine protection in this hi...
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research

Erratum to “Leadership as Tribal Leader”
Publication date: January 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 1Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - March 13, 2019 Category: Urology & Nephrology Source Type: research