Da First Day
Being the not so energetic guy, a bit nauseous, really sleepy and just plain old lazy here you have a recap by my charming, loving and most generous wife, Lu.DMSO - this is the chemical which Scott's stems cells were preserved in for the last 2 years....He, of course, cannot smell it and they put peppermint oil all around the room in little bowls to override the odor. Some say the smell resembles garlic...well, I love the smell of garlic, but not THIS garlic!! I've brought in a plug in diffuser and have Thieves essential oil in it see if that helps..."In cryobiology DMSO has been used as a ...
Source: Laughing Plasma Cells - July 4, 2015 Category: Cancer & Oncology Source Type: blogs
Rebirth Day 0
A Beautiful BirthdayA Mayo Sunset July 2nd, '15 is slowly coming to an end. Around noon today I received ~3.5 million of my own blood producing stem cells that have been frozen for a bit over 2 years here at Mayo Jacksonville. It is with a bit glee that I must admit the physical part has been a breeze. There is an unfamiliar emotion associated with free falling into the unknown. It's an odd juxtaposition of the very low vibration of insecurity, guilt and unworthiness mixed with a much more pleasant enthusiasm and positive expectation born of a belief or deeper knowledge I am unable to articulate. The hundreds of ...
Source: Laughing Plasma Cells - July 3, 2015 Category: Cancer & Oncology Source Type: blogs
Reboot Day 0
Earlier today I started my bone marrow reboot at 11 am (Yes it's July 1st so I tip my hat in honor of my friends celebrating Canada's birthday). The wonderful drug traveling through my body and soul is wiping out my blood cells. Every last one of those insidious myeloma cells is either already dead or soon will be. I'll do my best to give you a glimpse into my journey as it unfolds. There is no map. Let go and let the Universe unfold a new reality for me and everyone in my life. Just to give you and idea of how wonderfully geeky I really am you can read "Physicists at The Australian National University (ANU) have conducted...
Source: Laughing Plasma Cells - July 1, 2015 Category: Cancer & Oncology Source Type: blogs
More Trials
So I've added a couple more trials to an ever growing list. At last count I've had 12 different regimens over the last 10+ years half of which were clinical trials. There is definitely a "Aren't you special." feedback from all the attention clinical trial patients get.The ABT-199 trial ended after 5 cycles with evidence of progression seen via imaging (PET/CT). I have a tough clone to clobber. Illusive secretive beast that stops expressing any evidence of progression in the blood. Instead it just munches away at my bones with a relentlous incideous appetite.There is no doubt that the Oprozomib trial was not worth the extra...
Source: Laughing Plasma Cells - April 16, 2015 Category: Cancer & Oncology Source Type: blogs
ABT-199 Trial
I started a clinical trial of ABT-199 3 weeks ago. (sorta technical Myeloma Beacon EHA 2013 Congress Abstract P210 (Poster Presentation)) It is in combination with Velcade and Dex. The Dex is being reduced thank you very much!Three weeks on the protocol produced a 37% drop in my myeloma marker (Igg-Lambda Free Light Chains).It was easy easy easy just time consuming. I like to view is a behaviour disorder which compels me to drive almost an hour to an overpriced internet cafe'. I alway bring a book and laptop and don't bore easily soThe disorder then morphs into the Dex Pirate from which all living creatures shoul...
Source: Laughing Plasma Cells - August 27, 2014 Category: Cancer Source Type: blogs
Biannual Review
It is amazing to me that I can go 2 years without thinking about Laughing Plasma Cells. After the last post about my newly repaired arm I never went back to work. Instead I retired, moved to Amelia Island and am working on reinventing myself. As for the plumbers tape and drywall screws the repair was nothing short of amazing. Being a southpaw again has improved both my handwriting and my quality of life.I just do the myeloma thing. It does do me on occasion but life is good. I did a few clinical trials, a few slightly less common combinations and all kinds of whacky stuff as well. I even got John of God involved.After a li...
Source: Laughing Plasma Cells - June 24, 2014 Category: Cancer Source Type: blogs
I'll Take " Better "
Well as I predicted... Summer has officially arrived and so did the lab results from my 10th Revlimid cycle. " Better " without supplements despite a strong correlation with supplements in the prior 5 cycles. So would you spend the $4 bucks a day on those 2 dozen pills? If a few numbers and a single point of measurement were all that was needed to define success or failure life would be a lot simpler. Heck we wouldn ' t even need clinical trials at all. I do have to admit that I expected the trend to continue, but " Better " is better than worse even if not living up to my biases. 30% better is 50% better than 2 months a...
Source: Laughing Plasma Cells - June 23, 2009 Category: Cancer & Oncology Source Type: blogs
