Evidence to House of Commons Sci Tech Select Committee on Research Integrity
Sorry not to be in regular blogging mode at the moment. Here’s a video of our evidence session to parliament, where they are running an inquiry into research integrity. I think clinical trials are the best possible way to approach this issue. Lots of things in “research integrity” are hard to capture in hard logical […] (Source: badscience)
Source: badscience - December 5, 2017 Category: Science Authors: Ben Goldacre Tags: alltrials campaign publication bias Source Type: blogs

How do the world ’ s biggest drug companies compare, in their transparency commitments?
Here’s a paper, and associated website, that we launch today: we have assessed, and then ranked, all the biggest drug companies in the world, to compare their public commitments on trials transparency. Regular readers will be familiar with this ongoing battle. In medicine we use the results of clinical trials to make informed treatments about […] (Source: badscience)
Source: badscience - July 27, 2017 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs

Meaningful Transparency Commitments: the WHO Joint Statement from Trial Funders
By now I hope you all know about the ongoing global scandal of clinical trial results being left unpublished, and of course our AllTrials campaign. Doctors, researchers, and patients cannot make truly informed choices about which treatments work best if they don’t have access to all the trial results. Earlier this year, I helped out […] (Source: badscience)
Source: badscience - July 26, 2017 Category: Science Authors: Ben Goldacre Tags: bad science publication bias Source Type: blogs

How many epidemiologists does it take to change a lightbulb?
Robin Ince just asked if I know any epidemiologist lightbulb jokes. I wrote this for him. How many epidemiologists does it take to change a lightbulb? We’ve found 12,000 switches hidden around the house. Some of them turn this lightbulb on, some of them don’t; some of them only work sometimes; and some of them […] (Source: badscience)
Source: badscience - February 1, 2017 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs

How many epidemiologists does it take to change a lightbulb?
Robin Ince just asked if I know any epidemiologist lightbulb jokes. I wrote this for him. How many epidemiologists does it take to change a lightbulb? We’ve found 12,000 switches hidden around this house. Some of them turn this lightbulb on, some of them don’t; some of them only work sometimes; and some of them […] (Source: badscience)
Source: badscience - February 1, 2017 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs

“ Transparency, Beyond Publication Bias ” . A video of my super-speedy talk at IJE.
People often talk about “trials transparency” as if this means “all trials must be published in an academic journal”. In reality, true transparency goes much further than this. We need Clinical Study Reports, and individual patient data, of course. But we also need the consent forms, so we can see what patients were told. We need […] (Source: badscience)
Source: badscience - October 11, 2016 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs

You should totally watch this entire day of the IJE conference
Today marks the end of an era. The International Journal of Epidemiology used to be a typical hotchpotch of isolated papers on worthy subjects. Occasionally, some were interesting, or related to your field. Under Shah Ebrahim and George Davey-Smith it became like nothing else: an epidemiology journal you’d happily subscribe to with your own money, and read in […] (Source: badscience)
Source: badscience - October 7, 2016 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs

An audio interview with The Conversation, on smashing the walls of the Ivory Tower
The Conversation is a great media outlet, because it’s run by academic nerds, but made for everyone. I had a nice time chatting with them last week: we discussed transparency, data sharing, statins, research integrity, risk communication, culture shift, academic activism, and why we should kick through the walls of the ivory tower. Caution: contains nerds! theconversation.com/speaking-with-bad-pharma-author-ben-goldacre-about-how-bad-research-hurts-us-all-65800 (Source: badscience)
Source: badscience - October 3, 2016 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs

Sarepta, eteplirsen: anecdote, data, surrogate outcomes, and the FDA
The Duchenne’s treatment made by Sarepta (eteplirsen) has been in the news this week, as a troubling example of the FDA lowering its bar for approval of new medicines. The FDA expert advisory panel decided not to approve this treatment, because the evidence for any benefit is weak; but there was extensive lobbying from well-organised patients and, eventually, the FDA overturned the opinion of its own […] (Source: badscience)
Source: badscience - September 30, 2016 Category: Science Authors: Ben Goldacre Tags: bad science Source Type: blogs