Acinar Melanosis of the Bartholin Gland: A Report of 3 Cases

We report 3 patients with multiloculated cystic lesions of the vulvar vestibule exhibiting prominent melanocytic pigmentation. The current cases differ from a previous report of melanosis in a Bartholin gland cyst in that the population of melanocytes occupies the acinar structures of the gland, rather than a squamous-lined surface. A similar cell population is demonstrated by immunoperoxidase methods in a fourth patient’s nonpigmented gland, suggesting that melanin production may arise in a native, rather than metaplastic, cell population.
Source: International Journal of Gynecological Pathology - Category: Pathology Tags: Pathology of the Lower Tract: Original Articles Source Type: research