Prediction of Type 1 Diabetes at Birth Prediction of Type 1 Diabetes at Birth

Could metabolites in umbilical cord blood have a predictive role in the development of type 1 diabetes?Journal of Clinical Endocrinology &Metabolism
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

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Interim results from an ongoing multicenter clinical trial show that implanted pluripotent-stem-cell-derived endocrine progenitor cells can secrete insulin in patients with type 1 diabetes.Reuters Health Information
Source: Medscape Transplantation Headlines - Category: Transplant Surgery Tags: Diabetes & Endocrinology News Source Type: news
Condition:   Diabetes Mellitus, Type 1 Intervention:   Other: PRE-test Sponsors:   Universidad Iberoamericana;   Clemson University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: This is the first case report describing delayed seropositivity of CD and suggests that CD enteropathy may precede positive serology and could cause severe glucose dysregulation in patients with T1DM.PMID:34859874 | DOI:10.26355/eurrev_202111_27262
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Source Type: research
Talanta. 2022 Feb 1;238(Pt 1):122947. doi: 10.1016/j.talanta.2021.122947. Epub 2021 Oct 14.ABSTRACTAn ultrasensitive novel electrochemical nano-biosensor for rapid detection of insulin antibodies against diabetes antigens was developed in this research. The presence of insulin antibodies has been demonstrated to be a strong predictor for the development of type 1 diabetes in individuals who do not have diabetes but are genetically predisposed. The proposed nano-biosensor fabrication process was based on the optimized sequential electropolymerization of polyaniline and electrodeposition of gold nanoparticles on the surface ...
Source: Talanta - Category: Chemistry Authors: Source Type: research
Children diagnosed with type 2 diabetes appear significantly more likely to develop retinopathy and other ocular complications than children diagnosed with type 1 diabetes.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Conditions:   Type 1 Diabetes Mellitus;   Vitamin D Deficiency Intervention:   Dietary Supplement: vitamin D supplements (2000 IU/day) Sponsor:   Al-Azhar University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Research shows that harmful bacteria and inflammation in the mouth can indicate and even cause systemic conditions throughout the body.IRVINE, Calif., Nov. 18, 2021 /PRNewswire/ -- Leading dental support organization Pacific Dental Services® (PDS) has announced a new partnership with the American Diabetes Association® to increase awareness of the link between periodontal disease and diabetes, and how oral health providers can assist patients in preventing and managing this chronic health condition. The timing of this announcement coincides with American Diabetes Month ™, a month-long ...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
Pharmacol Res. 2021 Nov 29:106014. doi: 10.1016/j.phrs.2021.106014. Online ahead of print.ABSTRACTThe prevalence of diabetes is continuously increasing in the recent decades. Persistent hyperglycaemia, hyperinsulinemia and the subsequent oxidative stress result in diabetic complications, primarily categorized as microvascular (nephropathy, retinopathy and neuropathy) and macrovascular (cardiomyopathy) complications. The complications are prevalent in both type 1 and type 2 diabetic patients. Polyol pathway, elevated AGE production, PKC activation and hexosamine pathway are indeed the critical pathways involved in the progr...
Source: Cell Research - Category: Cytology Authors: Source Type: research
This study aimed to reveal the relationship between quality of life (QOL) and sleep quality in patients with type 1 diabetes mellitus (T1DM). Overall, 202 patients with T1DM were registered in our study, and 192 were eligible for analysis. Baseline characteristics and laboratory values were determined. Patients completed the Japanese versions of the Pittsburgh Sleep Quality Index (PSQI) and Diabetes Therapy-Related QOL (DTR-QOL) questionnaires. We investigated the relationship between the global PSQI and DTR-QOL total scores by using linear regression analysis. In univariate regression analysis, DTR-QOL total scores were a...
Source: Endocrine Journal - Category: Endocrinology Authors: Source Type: research
Condition:   Type 1 Diabetes Intervention:   Other: Biosampling Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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