Clinical Evidence of Current Irrigation Practices and the Use of Oral Antibiotics to Prevent and Treat Periprosthetic Joint Infection

During total joint arthroplasty, the contamination of the operative field with bacteria has historically been thought to be the major cause of early, acute periprosthetic joint infection (PJI).1 Aimed at reducing this bacterial load, surgeons have engaged in the use of irrigation and other adjuvants during surgery and before wound closure. These additives have varied in type, concentration, and mechanism for disrupting bacterial colonization. Antiseptics, antibiotic-infused irrigation, or soap-like surfactants are three main classifications for irrigation solutions.

Source: Orthopedic Clinics of North America - February 10, 2021 Category: Orthopaedics Authors: Jason Zlotnicki, Alexandra Grabrielli, Kenneth L. Urish, Kimberly M. Brothers Source Type: research