Systematic evaluation of evidence on veterinary viscoelastic testing Part 5: Nonstandard assays

ConclusionsNontraditional assays identified included thrombelastography (TEG)‐PlateletMapping (PM), functional fibrinogen assessment, and rapid‐TEG (r‐TEG). Direct veterinary evidence was found for only the ADP‐activated PM, which appears to generate valid data in dogs but not cats or horses. Arachidonic acid activated PM shows high variability and requires further assessment and validation in veterinary species. Functional fibrinogen assays may be performed in veterinary species but may require modification due to species differences in response to abciximab. While tissue factor (TF)‐activated TEG has been well described in the veterinary literature, the specific r‐TEG assay has not been assessed, but presumably would be effective for generating TEG tracings and values for maximum amplitude and angle in shorter periods of time than some traditional assays.

Source: Journal of Veterinary Emergency and Critical Care - January 10, 2014 Category: Veterinary Research Authors: Benjamin M. Brainard, Robert Goggs, Jose L. Mendez‐Angulo, Margaret C. Mudge, Alan G. Ralph, Bo Wiinberg Tags: Supplement Article Source Type: research