A controversial proposal: no more antibiotics for acne!

A controversial proposal: no more antibiotics for acne! Skin Therapy Lett. 2013 Aug;18(5):1-4 Authors: Muhammad M, Rosen T Abstract Administration of antibiotics, often for prolonged periods, has become the de facto standard of care for acne (and rosacea). However, the world is now facing a health crisis relating to widespread antibiotic resistance. The authors provide current evidence to suggest that dermatologists should consider a radical departure from standard operating procedure by severely curtailing, if not outright discontinuing, the routine and regular use of antibiotics for acne. PMID: 24305661 [PubMed - in process]
Source: Skin Therapy Letter - Category: Dermatology Authors: Tags: Skin Therapy Lett Source Type: research

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Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity. The pilosebaceous unit is a site for production and metabolism of a number of steroid hormones, including stress and sex hormones. This is an overview of the important role that the cutaneous HPA-like-axis plays in the pathogenesis and treatment of inflammatory pilosebaceous disorders, including acne, rosacea, seborrheic dermatitis, and hidradenitis suppurativa.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
This case series demonstrates how the use of photodynamic therapy, specifically via light-emitting diodes, can provide an effective, safe, and well-tolerated alternative treatment for acne rosacea.Journal of Medical Case Reports
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
AbstractPurpose of ReviewOngoing investigations of the human skin microbiome strongly suggest a connection to skin diseases and skin health. This review provides an overview of recent literature on the skin microbiome in relation to skin diseases, with a specific focus on common inflammatory skin conditions, such as atopic dermatitis, psoriasis, hidradenitis suppurativa, acne, and rosacea.Recent FindingsIn healthy subjects, the skin microbiome mediates fundamental processes involving the immune response and epidermal development and differentiation. Microbiome characteristics in inflammatory skin diseases differ depending ...
Source: Current Dermatology Reports - Category: Dermatology Source Type: research
Highlights from Monday, January 27, 2020 Acne and Rosacea 2020 New drugs, new data, and new insights into acne and rosacea—Maui Derm’s esteemed faculty shared their insights into the management of acne and rosacea. Lawrence Eichenfield, MD, presented on new therapies in acne. New therapies discussed by Dr. Eichenfield included trifarotene 50ug/g cream, which selectively […]
Source: Journal of Clinical and Aesthetic Dermatology - Category: Dermatology Authors: Tags: Meeting Coverage Maui Derm Daily News 2020 Source Type: research
Conditions:   Acne;   Acne Vulgaris;   Acne Keloidalis;   Acne Keloid;   Acne Conglobata;   Acne Rosacea;   Acne Inversa;   Acne Cystic;   Acne Pomade;   Acne Indurata;   Acne Papular;   Acne Tropica;   Acne Urticata;   Acne Fulminans;   Acne Follicular;   Acne Tropicalis;   Acn e Detergicans;   Acne Iodide;   Acne Varioliformis Intervention:   Other: No intervention Sponsor:   ProgenaBiome Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Human skin harbors a diverse group of microorganism that form complex communities and involve in a variety of complex molecular and cellular processes inside and outside the skin [1], and even influence gene expression in skin [2]. These microbiota interact directly with skin cells and play a central role in skin physiology and disease [3]. Many of evidence suggest a role for microorganisms in noninfectious skin diseases, such as atopic dermatitis (AD), rosacea, psoriasis, and acne [4]. However, the origin of many skin diseases is multifactorial and in some cases, such as the sensitive skin syndrome (SS), the role of micro...
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research
Publication date: 15 December 2019Source: International Journal of Pharmaceutics, Volume 572Author(s): Mohammed Elmowafy, Khaled Shalaby, Hazim M. Ali, Nabil K. Alruwaili, Ayman Salama, Mohamed F. Ibrahim, Mohamed A. Akl, Tarek A. AhmedAbstractThe main objective of this study was to develop, characterize and evaluate the potential use of dapsone-loaded nanostructured lipid carriers (NLCs) as a topical treatment for acne. Differently charged NLC formulations were successfully prepared using an emulsification/sonication method. The particle sizes ranged from 106.2 ± 5.6 nm to 151.3 ± 7.4 nm, and the...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Conclusions and implicationsSome preliminary evidence supports the use of zinc in the treatment of acne vulgaris and hidradenitis suppurativa; however, more research is needed with similar methodologies and larger sample sizes in these diseases. Further, zinc may be of some benefit in the treatment plan for atopic dermatitis and diaper dermatitis; however, additional studies should be conducted to further evaluate these potentially positive associations. To date, no evidence is available to suggest that zinc may be of benefit in rosacea and psoriasis; however, limited data are available evaluating the use of zinc in these conditions.
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Cannabidiol (CBD) oil and other products containing CBD are being touted as a natural, organic remedy for a wide range of women’s health concerns. Sellers of these products make many claims: CBD has calming effects on sleep, mood, and anxiety; eases hot flashes and improves bone density by balancing hormonal changes of menopause; and has anti-inflammatory properties that clear skin, cure acne, and calm rosacea. It’s promoted for PMS symptoms like bloating and mood swings. And CBD-infused lubricants claim to boost arousal and enjoyment of sex. So, how much of this is true? First, what is CBD? CBD is a major ingr...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Complementary and alternative medicine Drugs and Supplements Health Marijuana Women's Health Source Type: blogs
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