[Correspondence] Intermittent pneumatic compression in patients with stroke – Authors' reply

Johann Auer and colleagues question whether intermittent pneumatic compression (IPC) would be as effective if used with prophylactic anticoagulants. The CLOTS 3 trial was done in the UK, where the evidence-based national guidelines do not recommend routine use of anticoagulants for deep vein thrombosis (DVT) prophylaxis after stroke. David Barer highlights that although anticoagulants reduce (mainly asymptomatic) DVT, effects on pulmonary embolism are unclear and the increase in bleeds offsets any benefits, so there is no significant effect on survival or functional outcomes.
Source: LANCET - Category: Journals (General) Authors: Tags: Correspondence Source Type: research