Leading Innovation in Dermatology | Francesca Wuttke, Chief Digital Officer, Almirall

BY JESSICA DAMASSA, WTF HEALTH Almirall is a dermatology-focused pharmaceutical company based in Spain, and its investment in R&D for developing new therapeutics leads the way as the largest within the country’s pharma industry. It’s no surprise, then, that Almirall has also adopted a digital therapeutics and digital health strategy to augment it’s molecular innovations with a ‘beyond the pill’ approach. We sat down with Almirall’s first-ever Chief Digital Officer, Francesca Wuttke, to hear about the pharma company’s digital strategy which is centered on laying the framework for advanced analytical platforms that gather more health data about patients and skin health. For help and fresh ideas, Francesca has opened Almirall’s doors to health tech startups, launching a brand-new accelerator program cutely called ‘Almirall’s Digital Garden,’ to ‘seed’ and ‘grow’ innovative solutions. Are there lots of health startups out there that focus on treating psoriasis, acne, and other dermatological conditions? Francesca tells us what she hopes ‘reap’ from the Digital Garden and how she hopes her broader digital strategy will flourish at the boutique pharma company. Filmed at Barcelona Health Hub Summit in Barcelona, Spain, October 2019. Jessica DaMassa is the host of the WTF Health show &stars in Health in 2 Point 00 with Matthew Holt. Get a glimpse of the fu...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Tech Jessica DaMassa WTF Health Almirall Barcelona Health Hub Barcelona Health Hub Summit 2019 digital health Digital health funding digital therapeutics dtx Francesca Wuttke Pharma pharmaceuticals Source Type: blogs

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In medicine, we are trained to be colorblind and treat all patients equally, to the best of our ability. The irony is that in dermatology we have to take skin color into account, because the color of the skin affects the presentation of skin conditions. This is important to consider in order to make an accurate diagnosis and weigh the best treatment options. Appearance of skin conditions may vary based on skin color Skin conditions may look different on darker skin than on lighter skin. For example, many rashes, including allergic reactions to medication, appear pink or red on lighter skin. On a person with darker skin, an...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cosmetic surgery Health Skin and Hair Care Source Type: blogs
CONCLUSIONS: We found lack of evidence to address our review question: for most of our interventions of interest, we found no eligible studies. The neurokinin 1 receptor (NK1R) antagonist serlopitant was the only intervention that we could assess. One study provided low-certainty evidence suggesting that serlopitant may reduce pruritus intensity when compared with placebo. We are uncertain of the effects of serlopitant on other outcomes, as certainty of the evidence is very low. More studies with larger sample sizes, focused on patients with CPUO, are needed. Healthcare professionals, patients, and other stakeholders may h...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
AbstractIntroductionCutaneous body image (CBI) is a construct encompassing how individuals perceive their hair, skin, and nails. Negative CBI has been related to negative psychological outcomes and body image concerns. The first aim of our study was to further validate CBI as a construct. Second, as individuals with dermatologic conditions are at an increased risk for anxiety and depression, the study examined CBI as a mediator of the relationships between having a skin condition and anxiety and depression.MethodsA convenience sample of clinical participants with dermatologist-validated diagnoses of psoriasis, atopic derma...
Source: Dermatology and Therapy - Category: Dermatology Source Type: research
Human skin harbors a diverse group of microorganism that form complex communities and involve in a variety of complex molecular and cellular processes inside and outside the skin [1], and even influence gene expression in skin [2]. These microbiota interact directly with skin cells and play a central role in skin physiology and disease [3]. Many of evidence suggest a role for microorganisms in noninfectious skin diseases, such as atopic dermatitis (AD), rosacea, psoriasis, and acne [4]. However, the origin of many skin diseases is multifactorial and in some cases, such as the sensitive skin syndrome (SS), the role of micro...
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research
In this study, we discussed two cases who presented with low back pain after isotretinoin was used for the treatment of acne vulgaris. The patients did not have low back pain before isotretinoin use and did not have enthesitis, dactylitis, uveitis, psoriasis, recent infection, trauma, and family history spondylitis. HLA-B27 was negative. Bone-marrow edema was detected at the sacroiliac joint on magnetic resonance imaging. Because of these findings, sacroiliitis related to the drug was considered in our patients and isotretinoin treatments were discontinued. Because the patients ’ low back pain continued when they adm...
Source: Rheumatology International - Category: Rheumatology Source Type: research
This study demonstrated that O3 can activate cutaneous inflammasome in a redox dependent manner suggesting a possible role of this new pathway in pollution induced inflammatory skin conditions. PMID: 31778733 [PubMed - as supplied by publisher]
Source: Free Radical Biology and Medicine - Category: Biology Authors: Tags: Free Radic Biol Med Source Type: research
The increasing prevalence of Metabolic syndrome (MetS) is a worldwide health problem, and the association between MetS and skin diseases has recently attracted growing attention. In this review, we summarize the associations between MetS and skin diseases, such as psoriasis, acne vulgaris, hidradenitis suppurativa, androgenetic alopecia, acanthosis nigricans, and atopic dermatitis. To discuss the potential common mechanisms underlying MetS and skin diseases, we focus on insulin signaling and insulin resistance, as well as chronic inflammation including adipokines and proinflammatory cytokines related to molecular mechanism...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusions and implicationsSome preliminary evidence supports the use of zinc in the treatment of acne vulgaris and hidradenitis suppurativa; however, more research is needed with similar methodologies and larger sample sizes in these diseases. Further, zinc may be of some benefit in the treatment plan for atopic dermatitis and diaper dermatitis; however, additional studies should be conducted to further evaluate these potentially positive associations. To date, no evidence is available to suggest that zinc may be of benefit in rosacea and psoriasis; however, limited data are available evaluating the use of zinc in these conditions.
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Authors: Sheriff T, Lin MJ, Dubin D, Khorasani H Abstract Cannabis is increasingly being used world-wide to treat a variety of dermatological conditions. Medicinal cannabis is currently legalized in Canada, 31 states in America and 19 countries in Europe. The authors reviewed the literature on the pharmacology and use of cannabinoids in treating a variety of skin conditions including acne, atopic dermatitis, psoriasis, skin cancer, pruritus, and pain. Cannabinoids have demonstrated anti-inflammatory, antipruritic, anti-ageing, and antimalignancy properties by various mechanisms including interacting with the newly ...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
DISCUSSION: Dermatological conditions that require paraclinical assistance for diagnosis, hands-on examination, or treatment with either biologics or surgery will all result in high CPP. However, teledermatology still has a place in the treatment of high-CPP dermatoses in rural areas because there is no other alternative. For non-rural areas, CPP can be used as a way to identify those dermatoses that are not advantageous to treat using telemedicine, but instead best benefit from standard face-to-face consultation. PMID: 31545386 [PubMed - in process]
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
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