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CNN's Elizabeth Cohen speaks with researchers who are working to modernize the current process of making flu shots and develop a universal flu vaccine.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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CONCLUSION: This study can contribute to decision-making about potential prices for a chikungunya vaccine once it becomes available in Brazil. We demonstrated the relevance of the anchoring effect as a possible influence applied to the maximum value of the WTP associated with respondents' preference for a new vaccine. Finally, we encourage the development of a chikungunya virus vaccine to benefit the Brazilian population. PMID: 31815561 [PubMed - as supplied by publisher]
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
A multivalent HIV vaccine that consists of envelope protein (gp120 Env) and either DNA or NYVAC vectors during priming leads to early and potent IgG-binding antibody responses, according to results from the HIV Vaccine Trials Network (HVTN).Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: HIV/AIDS News Source Type: news
Publication date: Available online 9 December 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Qingtao Liu, Jing Yang, Xinmei Huang, Yuzhuo Liu, Kaikai Han, Dongmin Zhao, Lijiao Zhang, Yin LiAbstractAvian influenza subtype H9N2 infection is a mild but highly contagious disease that is associated with a decrease in the efficacy of vaccine interventions, and an increase in susceptibility to secondary infections in poultry. However, the immune evasion mechanism of H9N2 avian influenza viruses (AIVs) in chickens is poorly understood. Dendritic cells (DCs) are immune cells of major importance, involved in innate ...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
Canadian Journal of Microbiology, e-First Articles. Zika virus (ZIKV) is a mosquito-borne virus that was first isolated from Zika forest, Uganda, in 1947. Since its inception, major and minor outbreaks have been documented from several parts of world. Aedes spp. mosquitoes are the primary vectors of ZIKV, but the virus can also be transmitted through sexual practices, materno-fetal transmission, and blood transfusion. The clinical presentations of symptomatic ZIKV infections are similar to dengue and chikungunya, including fever, headache, arthralgia, retro-orbital pain, conjunctivitis, and rash. ZIKV often causes mild ill...
Source: Canadian Journal of Microbiology - Category: Microbiology Authors: Source Type: research
Contributor : Smita S IyerSeries Type : Expression profiling by high throughput sequencingOrganism : Macaca mulattaGenerating durable humoral immunity through vaccination depends upon effective interaction of follicular helper T cells (Tfh) with germinal center (GC) B cells. Th1 polarization of Tfh cells is an important process shaping the success of Tfh-GC B cell interactions by influencing co-stimulatory and cytokine-dependent Tfh help to B cells. However, the question remains whether adjuvant-dependent modulation of Tfh cells enhances HIV-1 vaccine-induced anti-Envelope (Env) antibody responses. We investigated whether ...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Macaca mulatta Source Type: research
No abstract available
Source: Nursing Made Incredibly Easy - Category: Nursing Tags: Department: Ask an Expert Source Type: research
W. Schaffner et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
(University of Maryland School of Medicine) Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli (ETEC), and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Contributors : Tingting Chen ; Caroline Blanc ; Maju Joe ; Todd L Lowary ; Jacqueline M AchkarSeries Type : Protein profiling by protein arrayOrganism : Homo sapiensIncreasing evidence suggests that antibodies (Abs) can have protective roles in M. tuberculosis (Mtb) infection but knowledge of the most relevant protective antigens and epitopes in humans is limited.Using novel glycan arrays, we establish that human serum IgG induced against the M. tuberculosis (Mtb) capsular polysacharide arabinomannan (AM) in natural Mtb infection is highly heterogeneous in its binding specificity and differs in both its reactivity to oligo...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Protein profiling by protein array Homo sapiens Source Type: research
In this study, prophylactic passive immunization was performed in a miniature swine model, using two vaccination-induced monoclonal antibodies (mAb), JEV-31 and JEV-169. These were selected as representatives for antibodies reactive with the major antigenic structures in the E protein of JEV and related flaviviruses. JEV-31 recognizes the lateral ridge of E protein domain III (EDIII) whilst JEV-169 has a broad footprint of binding involving residues throughout domains I (EDI) and II (EDII) of the E protein. Detection of neutralizing antibodies in the serum of immunized animals mimics the presence of neutralizing antibodies...
Source: Antiviral Therapy - Category: Virology Source Type: research
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