Advanced glaucoma at diagnosis: current perspectives

Eye, Published online: 18 November 2019; doi:10.1038/s41433-019-0637-2Advanced glaucoma at diagnosis: current perspectives
Source: Eye - Category: Opthalmology Authors: Source Type: research

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Authors: Zhou W, Yi Y, Gao Y, Dai J Abstract Accurate optic disc and optic cup segmentation plays an important role for diagnosing glaucoma. However, most existing segmentation approaches suffer from the following limitations. On the one hand, image devices or illumination variations always lead to intensity inhomogeneity in the fundus image. On the other hand, the spatial prior knowledge of optic disc and optic cup, e.g., the optic cup is always contained inside the optic disc region, is ignored. Therefore, the effectiveness of segmentation approaches is greatly reduced. Different from most previous approaches, we...
Source: Computational and Mathematical Methods in Medicine - Category: Statistics Tags: Comput Math Methods Med Source Type: research
[Pregnancy &glaucoma: SFO-SFG recommendations]. J Fr Ophtalmol. 2019 Dec 05;: Authors: Blumen-Ohana E, Sellem E PMID: 31813552 [PubMed - as supplied by publisher]
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
We present a stretchable sensor inside a contact lens capable of monitoring change in the curvature of cornea caused by IOP fluctuations. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Lab Chip latest articles - Category: Chemistry Authors: Source Type: research
Authors: Moreno Valladares A, Martínez de la Casa JM PMID: 31813589 [PubMed - as supplied by publisher]
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
Authors: Landi L, Casciaro F, Telani S, Traverso CE, Harris A, Verticchio Vercellin AC, Saint L, Iester M Abstract Purpose: To investigate potential associations between intraocular pressure (IOP) and cerebrospinal fluid pressure (CSFP) in patients with primary open-angle glaucoma (POAG) and healthy subjects. Methods: Forty-three subjects were recruited. Weight and height were measured to calculate body mass index (BMI), along with blood pressure, heart rate, visual acuity, and IOP. Biometrics exam, corneal pachymetry, peripapillary retinal nerve fiber layer (RNFL) thickness, and macular thickness were assessed...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Authors: Zhang X, Tenerelli K, Wu S, Xia X, Yokota S, Sun C, Galvao J, Venugopalan P, Li C, Madaan A, Goldberg JL, Chang KC Abstract BACKGROUND: Glaucoma, the number one cause of irreversible blindness, is characterized by the loss of retinal ganglion cells (RGCs), which do not regenerate in humans or mammals after cell death. Cell transplantation provides an opportunity to restore vision in glaucoma, or other optic neuropathies. Since transplanting primary RGCs from deceased donor tissues may not be feasible, stem cell-derived RGCs could provide a plausible alternative source of donor cells for transplant. OBJ...
Source: Restorative Neurology and Neuroscience - Category: Neurology Tags: Restor Neurol Neurosci Source Type: research
AbstractGlaucoma is the second leading cause of blindness worldwide. Even though significant advances have been made in its management, currently available antiglaucoma therapies suffer from considerable drawbacks. Typically, the success and efficacy of glaucoma medications are undermined by their limited bioavailability to target tissues and the inadequate adherence demonstrated by patients with glaucoma. The latter is due to a gradual decrease in tolerability of lifelong topical therapies and the significant burden to patients of prescribed stepwise antiglaucoma regimens with frequent dosing which impact quality of life....
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
Eye, Published online: 10 December 2019; doi:10.1038/s41433-019-0679-5How do different lighting conditions affect the vision and quality of life of people with glaucoma? A systematic review
Source: Eye - Category: Opthalmology Authors: Source Type: research
Dr Özcura raised several questions regarding our article on the effect of topical hypotensive medications to prevent an increase in intraocular pressure (IOP) after cataract surgery in eyes with glaucoma.1 Our study revealed that, compared with travoprost or timolol, brinzolamide administered to eyes with glaucoma immediately after phacoemulsification more effectively decreases the short-term IOP increase. We would like to address the questions raised by Dr Özcura.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Correspondence Source Type: research
CONCLUSION: Systems biological approaches can be used for the identification of antifibrotic drug candidates for the prevention of postoperative fibrosis and should be transferable by the investigating differential gene expression data of further ocular cells or tissues to other ophthalmological fields of application. PMID: 31805595 [PubMed - in process]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
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