Diagnosis Of Parvovirus B19 In Pregnancy Enhanced With Launch Of A Unique Highly Sensitive Molecular Assay

The molecular division of DiaSorin has launched the unique, highly sensitive Iam Parvo assay, a rapid quantitative molecular assay for use on the Liaison® Iam instrument. DiaSorin are the global leader in Parvovirus B19 serology testing, and the addition of this molecular assay expands its diagnostic portfolio for this potentially life-threatening virus. Parvovirus B19 (B19V) is a common childhood infection. It causes particular concern where a pregnant woman has had contact with a B19V infected individual, or where maternal B19V infection is suspected...
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

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ConclusionsB19V ‐PCR positivity was high and similar in both cases and controls. In our study B19V‐DNAemia was thus not seen to be associated with fatal outcome of pregnancy. The clinical significance of B19V‐DNA detection during pregnancy is uncertain. Caution is needed when diagnosing a B19V‐infection bas ed only on B19V‐DNAemia.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
AbstractTORCH, as coined by Nahmias et al. consists of Toxoplasmosis, other infections (includes, syphilis, HIV, Hepatitis viruses, varicella virus and Parvovirus B19), Rubella, Cytomegalovirus (CMV) and Herpes simplex virus. These infections are transmitted prenatally, perinatally, and postnatally through transplacental passage, contact with blood and vaginal secretions or from exposure to breast milk for CMV, HIV and HSV and infection generally manifests at birth, in infancy or in later years of life. The disease burden is maximum in low to middle-income countries. As treatment and prevention strategies are available for...
Source: Journal of Fetal Medicine - Category: Perinatology & Neonatology Source Type: research
Any infectious illness presenting with an eruption in a pregnant patient may be associated with an increased risk of fetal loss. The viruses that can infect the placenta during maternal infection and can be transmitted to the fetus and cause congenital disease include the rubella virus, the measles virus, the varicella zoster virus, parvovirus B19, human cytomegalovirus, arboviruses, and hepatitis E virus type 1. In addition, some bacteria responsible for exanthematous diseases, like Treponema pallidum, can be transmitted during pregnancy from the mother to the fetus and cause fetal loss.
Source: Clinics in Dermatology - Category: Dermatology Authors: Tags: Original Contributions Source Type: research
Abstract SUMMARYInfections during pregnancy that may cause congenital abnormalities have been recognized for decades, but their diagnosis is challenging. This was again illustrated with the emergence of Zika virus (ZIKV), highlighting the inherent difficulties in estimating the extent of pre- and postnatal ZIKV complications because of the difficulties in establishing definitive diagnoses. We reviewed the epidemiology, infection kinetics, and diagnostic methods used for Toxoplasma gondii, parvovirus B19, rubella virus, and cytomegalovirus (TORCH) infections and compared the results with current knowledge of ZIKV d...
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
​I have been seeing a lot of second disease and fifth disease—it's that time of year. School is back in session, and winter is just around the corner.The rash-numbering system for these diseases is now a historical footnote, but fifth disease is still commonly used by physicians to refer to erythema infectiosum, a parvovirus. I suspect that this system was created as a memory device for similar names and the obscure Latin terms used for these diseases. Erythema infectiosum is also easy to confuse with the many other erythema rashes such as erythema migrans, erythema marginatum, erythema toxicum, and erythema multif...
Source: M2E Too! Mellick's Multimedia EduBlog - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Authors: Keighley CL, Skrzypek HJ, Wilson A, Bonning MA, Gilbert GL Abstract Infections in pregnancy represent a challenging and often underappreciated area of concern for many specialists and general practitioners and can cause serious sequelae. Antenatal status should be highlighted on pathology request forms, as this serves to alert the laboratory of the need to store serum for an extended period. Prior antenatal specimens can be forwarded to other laboratories to enable testing in parallel with the more recent sample. Women with a confirmed, potentially vertically transmissible infection should be referred to a...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Abstract CONTEXT.—: Infections are the leading cause of perinatal and infant mortality in low-income and low-resource countries, which have a higher prevalence of infections. Definitive diagnosis of congenital and perinatal infections is largely dependent upon the results of laboratory tests. OBJECTIVE.—: To develop a multiplex nested polymerase chain reaction (PCR) for the simultaneous detection of 7 pathogens containing DNA in their genomes in suspected cases of congenital infection. DESIGN.—: Eligible participants were pregnant women with positive immunoglobulin M antibodies raised t...
Source: Archives of Pathology and Laboratory Medicine - Category: Laboratory Medicine Authors: Tags: Arch Pathol Lab Med Source Type: research
CONCLUSIONS: The characteristic clinical presentation in childhood was rash and fever, whereas in adults it was arthralgia. Anaemia is also frequent, but only severe in previous haematological disease. It should be pointed out that Erythrovirus B19 infection during pregnancy could severely affect the foetus. PMID: 31056091 [PubMed - in process]
Source: Anales de Pediatria - Category: Pediatrics Authors: Tags: An Pediatr (Barc) Source Type: research
CONCLUSION: Based on the findings of this study, prevalence of acute Parvovirus B19 infection was 0 and 2% based on Real-Time PCR and IgM tests, respectively. About 40% of pregnant women had experienced infection with this virus before. PMID: 30712919 [PubMed - as supplied by publisher]
Source: Journal of the National Medical Association - Category: General Medicine Tags: J Natl Med Assoc Source Type: research
Publication date: Available online 9 January 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Federico Prefumo, Anna Fichera, Nicola Fratelli, Enrico SartoriAbstractFetal anemia has been known for many years as a dangerous complication of pregnancy. Its most common causes are maternal alloimmunization and parvovirus B19 infection, although it can be associated with many different pathological conditions including fetal aneuploidies, vascular tumors, and arteriovenous malformations of the fetus or placenta and inherited conditions such as alpha-thalassemia or genetic metabolic disorders...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
More News: Erythema Infectiosum | Health | OBGYN | Parvovirus | Pregnancy