ACR Appropriateness Criteria® Gestational Trophoblastic Disease

Publication date: November 2019Source: Journal of the American College of Radiology, Volume 16, Issue 11, SupplementAuthor(s): Expert Panel on Women’s Imaging Panel, Kika M. Dudiak, Katherine E. Maturen, Esma A. Akin, Maria Bell, Priyadarshani R. Bhosale, Stella K. Kang, Aoife Kilcoyne, Yulia Lakhman, Refky Nicola, Pari V. Pandharipande, Rajmohan Paspulati, Caroline Reinhold, Stephanie Ricci, Atul B. Shinagare, Hebert Alberto Vargas, Bradford P. Whitcomb, Phyllis GlancAbstractGestational trophoblastic disease (GTD), a rare complication of pregnancy, includes both benign and malignant forms, the latter collectively referred to as gestational trophoblastic neoplasia (GTN). When metastatic, the lungs are the most common site of initial spread. Beta-human chorionic gonadotropin, elaborated to some extent by all forms of GTD, is useful in facilitating disease detection, diagnosis, monitoring treatment response, and follow-up. Imaging evaluation depends on whether GTD manifests in one of its benign forms or whether it has progressed to GTN. Transabdominal and transvaginal ultrasound with duplex Doppler evaluation of the pelvis are usually appropriate diagnostic procedures in either of these circumstances, and in posttreatment surveillance. The appropriateness of more extensive imaging remains dependent on a diagnosis of GTN and on other factors. The use of imaging to assess complications, typically hemorrhagic, should be guided by the location of clinical signs and symptoms.The ...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research