Tofacitinib therapy for the treatment of alopecia areata: Report of 11 patients

Background: Alopecia areata (AA) is a chronic disorder characterized by patchy loss of hair. Sometimes disease can be severe leading to loss of entire scalp and body hair. Management of these patients is very difficult with the available options of topical and systemic immunosuppressant agents. Tofacitinib, JAK3 inhibitor, is emerging as a promising drug for the management of severe and resistant cases of AA/totalis/universalis.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research