A cosmetic formulation containing a proprietary blend of ingredients improves skin barrier function and facial redness in vivo

Contact dermatitis, atopic dermatitis, rosacea, and acne are some of the many skin conditions attributed to a compromised skin barrier. Pathophysiological changes include elevated expression of cytokines, chemokines, impaired skin barrier function, vasodilation of blood vessels and increased blood flow. Reduced expression of epidermal differentiation proteins – filaggrin and occludin, elevated levels of proinflammatory cytokines and nitric oxide (NO), a key regulator in vasodilation of blood vessels, have been shown in individuals with atopic dermatitis.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research