Niacinamide reduces inflammatory response due to skin barrier disruption

Introduction: Impaired skin barrier function has been suggested to underlie sensitive skin. Sensitive skin triggers such as surfactant irritation or mechanical abrasion result in barrier damage and skin inflammation. In subjects with darker skin types, inflammation will also often result in the formation of postinflammatory hyperpigmentation (PIH). In vivo efficacy of niacinamide against inflammation caused by barrier damage has not yet been demonstrated.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research