CME Dermatology 19: Patchy Hair Loss.

[CME Dermatology 19: Patchy Hair Loss]. Praxis (Bern 1994). 2019 Jul;108(9):589-590 Authors: Lautenschlager SA, Lautenschlager S PMID: 31288654 [PubMed - in process]
Source: Praxis - Category: General Medicine Authors: Tags: Praxis (Bern 1994) Source Type: research

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Authors: Gupta AK, Carviel JL Abstract Background: Androgenetic alopecia (AGA) is a condition that affects most people at some point in their life, yet few treatments are available. Use of photobiomodulation is ideal due to the safety profile and lack of serious adverse effects. Therefore, the efficacy of photobiomodulation for AGA therapy was investigated.Methods: A meta-analysis was used to elucidate treatment efficacy. Additionally, a sub-analysis was performed to determine if the type of device used or if use of lasers versus light emitting diodes (LEDs) significantly impacted results.Results: Using hair densit...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
In conclusion, our data indicate an association between FASLG rs5030772 variation and AA. However, previously reported the association of FAS rs1800682 polymorphism with AA was not observed here. These findings highlight overlapping and distinct genetic polymorphisms in an Iranian cohort which might influence the susceptibility to AA. PMID: 31741398 [PubMed - as supplied by publisher]
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
The new services will address sexual health, skin conditions and hair loss.  
Source: mobihealthnews - Category: Information Technology Source Type: news
Source: Application of Clinical Genetics - Category: Genetics & Stem Cells Tags: The Application of Clinical Genetics Source Type: research
A variety of medications can cause hair loss as an unintended side effect. Learn about whether the hair will regrow and how to treat hair loss here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news
Publication date: Available online 20 November 2019Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): A. Guerra-Tapia, A. Buendía-Eisman, J. Ferrando Barbera, en representación del grupo de validación Hair Specific Skindex 29AbstractBackground and objectiveWork has already been done on validating the cross-cultural adaptation of the hair-specific Skindex-29 questionnaire (HSS-29) into Spanish. This questionnaire measures the impact of female-pattern hair loss on health-related quality of life (HRQoL). The aim of this study was to complete the validation process by testing the questi...
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Mengxu Ge, Chuncheng Liu, Lei Li, Miaomiao Lan, Yingying Yu, Lijie Gu, Yang Su, Kuo Zhang, Yuying Zhang, Tongtong Wang, Chang Liu, Fan Liu, Min Li, Lei Xiong, Kun Wang, Ting He, Yunping Dai, Yaofeng Zhao, Ning Li, Zhengquan YuSummaryHair follicle stem cells (HFSCs) and subsequent generations of matrix progeny make lineage choices by responding to spatiotemporal signals; however, the cues driving that specification are not well understood. Here, we demonstrate that the dynamics of microRNA (miR)-29 expression are inversely proportional to H...
Source: Cell Reports - Category: Cytology Source Type: research
The skin homeostasis is controlled by a complex interplay between tightly regulated transcription factors and signaling pathways. MYB is a transcription factor expressed in hair follicle progenitor cells and found overexpressed in adnexal skin tumors. However, the biological consequences of deregulated MYB expression in the skin remain poorly understood. To address this, we generated transgenic mice that overexpress MYB in epidermal and follicular keratinocytes. These mice exhibited a normal hair coat after birth, but gradually developed alopecia, accompanied by altered follicular differentiation, disrupted hair cycle and ...
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
The increasing prevalence of Metabolic syndrome (MetS) is a worldwide health problem, and the association between MetS and skin diseases has recently attracted growing attention. In this review, we summarize the associations between MetS and skin diseases, such as psoriasis, acne vulgaris, hidradenitis suppurativa, androgenetic alopecia, acanthosis nigricans, and atopic dermatitis. To discuss the potential common mechanisms underlying MetS and skin diseases, we focus on insulin signaling and insulin resistance, as well as chronic inflammation including adipokines and proinflammatory cytokines related to molecular mechanism...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Leucin-rich repeats and immunoglobulin-like domains 1 (LRIG1), one of three members of a transmembrane protein family (LRIG1-3), has attracted attention due to its impact on receptor tyrosine kinases (RTKs) such as the epidermal growth factor receptor (EGFR/ERBB1/HER1) and the other members of the ERBB-receptor family (ERBB2-4/HER2-4) [1]. In human skin, LRIG1 is expressed in the interfollicular epidermis (IFE) and hair follicles (HF) [2], and promotes stem cell (SC) quiescence [3]. A disturbed balance of proliferation and differentiation of HF-SCs can be observed in various skin diseases, including psoriasis and alopecia.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
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