Random Codon Re-Encoding Induces Stable Reduction Of Replicative Fitness Of Chikungunya Virus In Primate And Mosquito Cells

A promising new method for next-generation live-attenuated viral vaccines against Chikungunya virus Researchers have successfully applied a novel method of vaccine creation for Chikungunya virus (CHIKV) using a technique called large scale random codon re-encoding.� Using this approach, a group from the UMR_D 190, Emerging viruses Department in Marseille, France in collaboration with the University of Sydney, Australia, demonstrated that the engineered viruses exhibit a stable phenotype with a significantly decreased viral fitness (i.e...

Source: Health News from Medical News Today - February 21, 2013 Category: Consumer Health News Tags: Tropical Diseases Source Type: news