Genapsys ' Base Caller: Mysterious, But Not Ideal?

WhenI wrote about Genapsys' pre-print on their sequencing system the other night, I intended that to be the last I wrote until some major news from them.   But after launching that into the great Internet ether,  I found myself lying awake wondering if a very simple idea had any merit.  Painfully simple -- I almost didn't pursue it because it was so simple and obvious.   But, it turns out it appears to have merit -- there may be an obvious route to improving the accuracy of Genapsys' basecalling on homopolymers.   And that also took me into ground I've thought about before -- going back to my first year at Codon Devices over a decade ago -- on the challenge of modeling sequence quality.Read more »
Source: Omics! Omics! - Category: Bioinformatics Authors: Source Type: blogs