Earlier Onset of Type 1 Diabetes Linked to Weaker Bones Earlier Onset of Type 1 Diabetes Linked to Weaker Bones

Postmenopausal women with type 1 diabetes (T1D) have lower volumetric bone-mineral density (vBMD) than their diabetes-free peers, and bone-quality deficits may be even greater for those who developed the disease before age 20, according to new findings.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

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This study aims to investigate associations between glycated haemoglobin (HbA1c), glycated albumin (GA) and fructosamine with neonatal birthweight in gestational diabetes mellitus (GDM). The prospective cohort consisted of 82 women with GDM and their newborns, enrolled between November 2016 and September 2017. Considering neonatal birthweight and birthweights ≥90th percentile for gestational age as outcomes, linear and logistic regression models were used, respectively. Fructosamine (R2=0.62) and GA (R2=0.61) performed very similarly between them and best than HbA1c (R2=0.58). The added value of GA or fructosamine to Hb...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Pregnant women with type 1 diabetes had an increased risk for preterm birth, which rose with worsening glycemic control. The results highlight the importance of achieving recommended HbA1c targets.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
(Karolinska Institutet) Pregnant women with type 1 diabetes are at increased risk of delivering their baby prematurely. The risk increases as blood sugar levels rise, however women who maintain the recommended levels also risk giving birth prematurely. These are the findings from researchers at Karolinska Institutet and the Sahlgrenska Academy in Sweden, published in Annals of Internal Medicine.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
James Norton, 33, who plays Sidney Chambers in Grantchester, has type 1 diabetes and has to have a glucose monitor stuck out of sight on his bottom if he is filming a topless scene.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Source: Diabetologia - Category: Endocrinology Source Type: research
Regulatory T (Treg) cells play a key role in immune system homeostasis by suppressing detrimental immune responses against self-proteins, in particular in the intestine.1 Patients with mutations in the gene FOXP3 display a severe defect of Treg-cell function that results in IPEX syndrome (OMIM 304790) characterized by impaired immune tolerance and multiorgan autoimmunity. Dermatitis, type 1 diabetes, and in particular autoimmune enteropathy are hallmarks of the syndrome. Intestinal Treg cells normally suppress immune responses against harmless dietary antigens and commensal microorganisms, but the intestinal self-proteins ...
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Letter to the Editor Source Type: research
This study presents findings from a large sample with extensive clinical phenotyping—allowing us to examine the relationships of insulin resistance with a number of key psychopathological, cognitive, and functioning measures, using multivariate methods to assess the relative contributions of different factors to metabolic abnormalities. PwS often have many risk factors for metabolic abnormalities: lifestyle habits, medications, and underlying biological mechanisms including inflammation and oxidative stress. Treatment and prevention of metabolic abnormalities in PwS can be particularly challenging due to these multip...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
MONDAY, April 22, 2019 -- For women with type 1 diabetes (T1D), the risk for preterm birth is strongly associated with periconceptional hemoglobin A1c (HbA1c) level, according to a study published online April 22 in the Annals of Internal...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
AbstractPurpose of ReviewThe aims of this review are to summarize recent data on mortality and cardiovascular disease (CVD) in type 1 and type 2 diabetes and to determine the interventions that could have contributed to a reduction in mortality.Recent FindingsRecent studies found a downward trend in mortality and CVD among both diabetics and non-diabetics worldwide over the last few decades. The decline among diabetics is steeper than that among non-diabetics. Despite a parallel trend of decline, an approximately twofold difference in mortality and CVD between the two populations remains.SummaryA greater emphasis on glycem...
Source: Current Cardiology Reports - Category: Cardiology Source Type: research
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
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