Hepatitis C in England 2019

This report summarises the current data, the impact of action plans in England to drive down mortality from hepatitis C virus infection and to reduce the number of new infections, and outline the actions required to make further progress.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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This study evaluates NLR in a large cohort of HCC patients. Methods: We retrospectively reviewed 789 HCC cases (1993-2017) for demographics, tumor characteristics, treatment, and survival. NLR was stratified into NLR ≥1.5 and NLR ≥3 and analyzed for correlation with American Joint Committee on Cancer (AJCC) and Barcelona Clinic Liver Cancer (BCLC) stages. In 235 patients who underwent liver resection, survival and recurrence were evaluated by NLR. Results: In 789 HCC cases, mean NLR was increased with advanced AJCC and BCLC stages. Hepatitis C patients were less likely to have NLR ≥1.5 and ≥3. Non-alcoh...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Publication date: May 2019Source: American Journal of Kidney Diseases, Volume 73, Issue 5Author(s):
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Publication date: May 2019Source: American Journal of Kidney Diseases, Volume 73, Issue 5Author(s):
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Publication date: May 2019Source: American Journal of Kidney Diseases, Volume 73, Issue 5Author(s):
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
This article summarizes the prevalence and risk factors of hepatitis B and C reactivation in patients with rheumatic diseases undergoing biologic and targeted therapies, as well as the recommendations for screening, monitoring, and treatment of these infections.
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
Conclusions: IC patients were not at a significant increased risk for perioperative complications, postoperative infections, or readmissions, but they were at higher risk of reoperation.
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Original Research Source Type: research
Jair L. Siqueira-Neto Zika virus (ZIKV), an emerging flavivirus that causes neurodevelopmental impairment to fetuses and has been linked to Guillain-Barré syndrome continues to threaten global health due to the absence of targeted prophylaxis or treatment. Nucleoside analogues are good examples of efficient anti-viral inhibitors, and prodrug strategies using phosphate masking groups (ProTides) have been employed to improve the bioavailability of ribonucleoside analogues. Here, we synthesized and tested a small library of 13 ProTides against ZIKV in human neural stem cells. Strong activity was observed for ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Source: BMJ News - Category: General Medicine Source Type: research
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b00143
Source: Journal of Medicinal Chemistry - Category: Chemistry Authors: Source Type: research
Opioids and infectious diseases, PrEP and STI risk, new oral Rx for C diff, and a shortage of ID specialists. We summarize studies, commentaries,   and reports on these topics and more.
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Hepatitis C Infectious Disease Source Type: news
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