Investigating the effects of Pirfenidone on TGF- β1 stimulated non-SMAD signaling pathways in Dupuytren’s disease -derived fibroblasts

Dupuytren ’s disease (DD) is a progressive, debilitating condition of the hand that can eventually cause contractures of the affected fingers. Transforming growth factor- β1 (TGF-β1) has been reported to play a...

Source: BMC Musculoskeletal Disorders - March 30, 2019 Category: Orthopaedics Authors: Chaoming Zhou, Yael Zeldin, Mark E. Baratz, Sandeep Kathju and Latha Satish Tags: Research article Source Type: research