Indurated dusky red swelling on the forearm of an infant: Tufted angioma

We present a case of 8-months-old infant with TA over the right forearm with classical clinical, histoptahological and immunohistochemistry features.
Source: Indian Journal of Dermatology - Category: Dermatology Authors: Source Type: research

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In this report, we present a 4.5 year old girl diagnosed with H syndrome based on genetic investigation.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Localized hypertrichosis with traumatic panniculitis is considered a rare condition. Previous articles have reported occurrence in females aged between 20 and 35 years. Possible mechanisms of trauma-induced localized hypertrichosis include hyperemia and angiogenesis induced by local inflammation, which can alter the hair growth cycle. The presence of inflammatory cells and lipomembranous changes on histopathology can support the diagnosis. We herein present a 35-year-old female patient with localized hypertrichosis following blunt trauma.Case Rep Dermatol 2019;11:180 –186
Source: Case Reports in Dermatology - Category: Dermatology Source Type: research
ConclusionCyclosporine is a safe and effective treatment for PPP with few adverse effects, which might be related to the regulation of IL-23 and TNF- α.
Source: Dermatology and Therapy - Category: Dermatology Source Type: research
We report de novo missense variants in KCNN3 in three individuals with typical clinical features of ZLS. KCNN3 (SK3/KCa2.3) constitutes one of three members of the small-conductance Ca2+-activated K+ (SK) channels that are part of a multiprotein complex consisting of the pore-forming channel subunits, the constitutively bound Ca2+ sensor calmodulin, protein kinase CK2, and protein phosphatase 2A.
Source: The American Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
Conclusion and Perspectives Since their cloning 20 years ago, the physiological importance of TREK-1 channels has continued to grow (Figure 3). Today, TREK-1 channels have been shown to be important and their presence is essential in a number of physiopathological processes. Their involvement in these different processes demonstrate the necessity to design pharmacological modulators, activators or inhibitors, of these channels to correct any TREK-1-related dysfunctions. Despites a number of studies and many molecule screenings, only few putative new drugs were identified. The activators belonging to the ML and BL series ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
AbstractBecker ’s nevus is a common pigmented dermatosis, usually featured by ipsilateral pigmented patch with hypertrichosis. Becker’s nevus is often treated with various types of lasers although other regimens are available. However, clinical outcomes appear inconsistent among studies. To summarize the clini cal outcomes of Becker’s nevus treated with lasers via literature review. A variety of lasers had been used alone or in combination to treat Becker’s nevus. Laser wavelengths used for Becker’s nevus ranged from 504 to 10,600 nm, while the number of treatment varied from 1 to 12 sess...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Lalit Patidar, from Ratlam in central India, was born with a condition called hypertrichosis which causes excessive hair growth on his face – the disorder is also known as 'werewolf syndrome'.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Mucous Membrane Pemphigoid is a rare and debilitating disease that affects bodily mucous membranes, especially those of the eyes and oropharynx. It results in ocular surface disease leading to scarring, lid abnormalities and vision loss. Hypertrichosis associated with increased local prostaglandin levels due to topical medication or other types of ocular inflammation has been well documented. We hypothesize that mucous membrane pemphigoid also increases local prostaglandin levels and this increased concentration of prostaglandin contributes to an enhanced lash growth rate.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Conclusion: This study not only extended the clinical and mutation spectrum ofSLC29A3 in H syndrome, but also showed that short children should be assessed according to the guidelines for short stature in children.Horm Res Paediatr
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research
We report on 7 burn patients who developed hypertrichosis following application of pressure garment/silicone therapy to prevent hypertrophic scarring.
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Burn Surgery and Research Source Type: research
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