Woman's feet swell to 'THREE times their normal size'

Tawheeda Jan, from India, has lymphatic filariasis - a condition more commonly known as elephantiasis. The 21-year-old, who claims she was born with the condition, is now housebound.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Conditions:   Lymphatic Filariasis Elimination by Mass Drug Administration;   Monitoring and Evaluation of Mass Drug Administration for Lymphatic Filariasis;   Acceptability of Mass Drug Administration for Lymphatic Filariasis Intervention:   Other: Observational Sponsors:   University Hospitals Cleveland Medical Center;   Case Western Reserve University;   Washington University School of Medicine;   Papua New Guinea Institute for Medical Research;   Papua New Guinea ENB ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
[WHO] The Angolan Ministry of Health, with technical support from WHO, carried out a data review and validation of five key Neglected Tropical Diseases. namely lymphatic filariasis (LF), onchocerciasis (Onco), schistosomiasis (SCH), geohelminthiasis or soil-borne helminths (HTS) and trachoma
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[WHO] WHO Eritrea has provided a training to over 35 health workers as part of strengthening their capacities in the control and elimination of the disease lymphatic filariasis at the conference hall of the National confederation of Eritrean Workers from 30 September up to 4 October 2019.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
We present the results of a school-based survey, which targeted 1,014 students in all 13 elementary schools in WAF. From a fingerprick, the circulating filarial antigen (CFA) positivity was checked for grade 2-5 students using BinaxNOW filariasis test (immunochromatographic test). Of 935 children tested, three were positive for CFA in two schools. At the territory level, this was below the critical cutoff of nine cases, if the whole territory was considered as a single evaluation unit. The prevalence of CFA in WAF is less than 1%, reaching the goal for LF elimination set by the WHO. We were able to recommend stopping LF MD...
Source: Am J Trop Med Hyg - Category: Infectious Diseases Authors: Tags: Am J Trop Med Hyg Source Type: research
Conclusions and significanceLimb volume measurements by 3DIS are accurate and reproducible, and this technique is feasible for use in patients ’ homes. We have developed practical suggestions for optimal outcomes with 3DIS. Duplicate measurements should be performed and repeat assessments should be done at approximately the same time of day to minimize bias. Duplicate measures that vary by more than 8% should prompt review of scanning te chnique with a repeat measurement. With proper training and attention to technique, 3DIS can be a valuable tool for healthcare workers who work with lymphedema patients.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
AbstractTo achieve the elimination of onchocerciasis transmission in all African countries will entail enormous challenges, as has been highlighted by the active discussion around onchocerciasis intervention strategies and evaluation procedures in this journal.Serological thresholds for onchocerciasis elimination, adapted for the African setting, need to be established. The Onchocerciasis Technical Advisory Subgroup of the World Health Organization is currently developing improved guidelines to allow country elimination committees to make evidence-based decisions. Importantly, onchocerciasis-related morbidity should not be...
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research
AbstractBefore the founding of the People ’s Republic of China 70 years ago, both extreme poverty and parasitic infections and other neglected tropical diseases were highly prevalent. Owing to social development, particularly economic reforms since the 1980s, poverty has since been dramatically reduced, and China became increasingly urb anized and industrialized. In parallel, China’s economic transformation translated into similar and remarkable reductions in neglected tropical diseases. Qian and colleagues report in their review published inInfectious Diseases of Poverty, the elimination or near elimina...
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research
AbstractSince the founding of the People ’s Republic of China in 1949, considerable progress has been made in the control and elimination of the country’s initial set of 11 neglected tropical diseases. Indeed, elimination as a public health problem has been declared for lymphatic filariasis in 2007 and for trachoma in 2015. The remaini ng numbers of people affected by soil-transmitted helminth infection, clonorchiasis, taeniasis, and echinococcosis in 2015 were 29.1 million, 6.0 million, 366 200, and 166 100, respectively. In 2017, after more than 60 years of uninterrupted, multifaceted sch...
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research
Conclusions/SignificanceThis is the first global study of changes in gene expression associated with AEs after treatment of lymphatic filariasis. Changes in cytokines were consistent with prior studies and with the RNAseq data. These results suggest thatWolbachia lipoprotein is involved in AE development, because it activates TLR2-TLR6 and downstream NF- κB. Additionally, LPS Binding Protein (LBP, which shuttles lipoproteins to TLR2) increased post-treatment in individuals with AEs. Improved understanding of the pathogenesis of AEs may lead to improved management, increased MDA compliance, and accelerated LF elimination.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Nat. Prod. Rep., 2019, Advance Article DOI: 10.1039/C9NP00042A, Review ArticleRa úl G. Saraiva, George Dimopoulos In this review, we discuss the merits of using bacterial metabolites – including those secreted by the mosquito microbiota – to combat malaria and filariasis, as well as dengue fever and other arboviral diseases. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Nat. Prod. Rep. latest articles - Category: Chemistry Authors: Source Type: research
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