Platelet-Rich Fibrin as a Grafting Material in Periapical Surgery: A Case Series.

Platelet-Rich Fibrin as a Grafting Material in Periapical Surgery: A Case Series.
Int J Periodontics Restorative Dent. 2018 Dec 14;:
Authors: Kulkarni MR, Mohan J, Bakshi PV
Abstract
Positive effects of platelet-rich fibrin (PRF) on soft tissue healing are well documented, but its role in hard-tissue healing remains contested. The present case series documents the use of PRF as the sole grafting material in periapical bone defects. PRF was prepared and condensed into the bone defects after debridement. The defects were then covered with a collagen membrane and wound closure was performed. In all three cases presented in this report, excellent bone fill was observed in the periapical defects. The observed benefit may be due to the role of fibrin in initial clot stabilization. The elaboration of various growth factors by the platelets and leukocytes in the PRF clot may also play a role.
PMID: 30550610 [PubMed - as supplied by publisher]

Source: International Journal of Periodontics and Restorative Dentistry - December 16, 2018 Category: Dentistry Tags: Int J Periodontics Restorative Dent Source Type: research