Applying Recent A1C Recommendations in Clinical Practice Applying Recent A1C Recommendations in Clinical Practice

Three clinical guidelines were published in 2018 that address the use of A1C in the diagnosis and management of diabetes mellitus--but they don't all agree. Explore the controversy in this paper.U.S. Pharmacist
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pharmacist Journal Article Source Type: news

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Let‑7a‑5p may participate in the pathogenesis of diabetic nephropathy through targeting HMGA2. Mol Med Rep. 2019 Mar 19;: Authors: Wang T, Zhu H, Yang S, Fei X Abstract Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus (DM), and has been demonstrated as one of the major causes of renal failure. In a previous study, it was noted that microRNA let‑7a‑5p was downregulated in DN; however, the underlying mechanism requires additional investigation. The aim of the present study was to investigate the roles of let‑7a‑5p in the pathogenesis of DN and its associa...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Liu Z, Yu X, Tong C, Qi H Abstract Gestational diabetes mellitus (GDM) incidence is increasing worldwide. In the present study, the effects of metformin on high fat diet (HFD)‑induced renal dysfunction were investigated in GDM mice. In addition, the molecular mechanisms underlying metformin function were examined. GDM was induced by feeding pregnant mice a HFD, and mice were treated with two different doses of metformin (300 and 600 mg/kg/day) or PBS between embryonic day 11.5 (E11.5) and E17.5. The pregnant mice at E18.5 were utilized to analyze the effects of metformin on renal dysfunction. Renal ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
The objective of this report was to summarize current knowledge of CC, squamous intraepithelial lesions, and human papillomavirus (HPV) infection in non-HIV immunocompromised women to determine best practices for CC surveillance in this population and provide recommendations for screening. We evaluated those with solid organ transplant, hematopoietic stem cell transplant, and a number of autoimmune diseases. A panel of health care professionals involved in CC research and care was assembled to review and discuss existing literature on the subject and come to conclusions about screening based on available evidence and expe...
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research
Publication date: Available online 21 March 2019Source: Food Science and Human WellnessAuthor(s): Chenggang Zhang, Wenjing Gong, Zhihui Li, Dawen Gao, Yan GaoAbstractHuman wellness is the ultimate goal of our efforts in improving the human life. Special foods are undoubtedly important in achieving human wellness. However, overeating significantly leads to obesity and diabetes. These chronic diseases will in turn affect the human wellness. Therefore, “dietary restriction and proper exercise” were introduced in the human daily life. Different foods cause various effects on the human health. The diversification of...
Source: Food Science and Human Wellness - Category: Food Science Source Type: research
ConclusionsMetformin is a clinically effective, inexpensive and safe drug for treating gestational diabetes mellitus.
Source: The Journal of Obstetrics and Gynecology of India - Category: OBGYN Source Type: research
Source: International Urogynecology Journal - Category: OBGYN Source Type: research
Abstract: Prediabetes continues to be a national and worldwide health concern, affecting 84 million adults in the US. Early identification and intervention have been successful in delaying and/or preventing the progression to type 2 diabetes mellitus (T2DM). To curb the increasing prevalence of T2DM, recognizing the importance of identifying and managing prediabetes is paramount.
Source: Nursing - Category: Nursing Tags: Feature: CE Connection Source Type: research
ConclusionsThese data suggested that JLD could improve metabolic disorders in associated with activation of BAT thermogenesis via enhancement of mitochondrial biogenesis and fatty acid oxidation metabolism, thus providing a new pharmacological evidence for the clinical usage of JLD in T2DM treatment.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
CONCLUSION: In Portugal, the level of prescribing of non-steroidal anti-inflammatory drugs to patients with diabetes mellitus should be reduced, particularly in the subgroups identified with higher prescription and with higher risk of progression to stage 5 chronic kidney disease. PMID: 30896392 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
PMID: 30897598 [PubMed - in process]
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
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