Sudan: Medics - Chikungunya Infections On the Rise in Port Sudan

[Radio Dabanga] Port Sudan -Health sources have pointed to a rise of rates of chikungunya fever infections in eastern districts of Port Sudan in Red Sea state.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Publication date: Available online 18 October 2019Source: Microchemical JournalAuthor(s): Welma T.S. Vilar, Mayara F. Barbosa, Licarion Pinto, Mário César Ugulino de Araújo, Márcio José Coelho PontesABSTRACTAedes aegypti mosquitoes are vectors of diseases such as dengue, chikungunya, zika and yellow fever. With the increase in the incidence of these diseases the population has resorted to the use of repellents searching to protect themselves from mosquito attack. The Brazilian market offers a wide variety of products with different active principles in varying levels of concentration, tim...
Source: Microchemical Journal - Category: Chemistry Source Type: research
a GP Abstract Chikungunya virus (CHIKV) is an arbovirus that emerged in the Americas in 2013. Infection with CHIKV is symptomatic in most of the cases and patients can develop chronic arthralgia that lasts from months to years in over 40% of the cases. The East-Central-South Africa (ECSA) genotype was introduced in Brazil in 2014, in Bahia State. Here we report the circulation of the CHIKV ECSA genotype in Piaui State, Northeast Brazil, during the years 2016-2017. The phylogenetic analysis revealed a single introduction of this lineage probably in 2015 and its maintenance at least until 2017. This analysis has als...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
[Radio Dabanga] Kassala -The Sudan Central Doctors' Committee reports widespread prevalence of chikungunya* and dengue fever in Kassala state, pointing out that 48 per cent of the total pathology samples tested positive.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
AbstractAlphaviruses, including Chikungunya (CHIKV) and Venezuelan equine encephalitis virus (VEEV), are among the leading causes of recurrent epidemics all over the world. Alphaviral non ‐structural protein 1 (nsP1) orchestrates the capping of nascent viral RNA via its S‐adenosyl methionine‐dependent N‐7‐methyltransferase (MTase) and guanylyltransferase activities. Here, we developed and validated a novel capillary electrophoresis (CE)‐based assay for measuring the MTase activity of purified VEEV and CHIKV nsP1. We employed the assay to assess the MTase inhibition efficiency of a few adenosine analogs and iden...
Source: FEBS Letters - Category: Biochemistry Authors: Tags: RESEARCH ARTICLES Source Type: research
Conclusions/significanceOur study shows that exposure to bites ofAe.albopictus orAe.aegypti evokes in mice species-specific IgG responses to al34k2 or ae34k2, respectively. Deeper understanding of duration of antibody response and validation in natural conditions of human exposure toAedes mosquitoes are certainly needed. However, our findings point to the al34k2 salivary protein as a promising potential candidate for the development of immunoassays to evaluate human exposure toAe.albopictus. This would be a step forward in the establishment of a serological toolbox for the simultaneous assessment of human exposure toAedes ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
The Asian tiger mosquito, Aedes (Stegomyia) albopictus (Skuse) is an important worldwide invasive species and can be a locally important vector of chikungunya, dengue and, potentially, Zika. This species is nativ...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
This study provides valuable data on sex-specific expression of protein-coding genes and lncRNAs in adult Ae. albopictus, which will guide further studies aimed at understanding sex development and determination mechanisms in this species.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusions and significanceAlthough IRM should be a fixture of all vector control programs, it is currently often absent from the strategic plans to control mosquito-borne diseases, especially arboviruses. Experiences from other public health disease vectors and agricultural pests underscore the need for urgent action in implementing IRM for invasiveAedes mosquitoes. Based on a plan developed for malaria vectors, here we propose some key activities to establish a global plan for IRM inAedes spp.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
by Andrew J. Monaghan, Rebecca J. Eisen, Lars Eisen, Janet McAllister, Harry M. Savage, John-Paul Mutebi, Michael A. JohanssonAedes (Stegomyia) aegypti (L.) andAe.(Stegomyia) albopictus (Skuse) mosquitoes can transmit dengue, chikungunya, yellow fever, and Zika viruses. Limited surveillance has led to uncertainty regarding the geographic ranges of these vectors globally, and particularly in regions at the present-day margins of habitat suitability such as the contiguous United States. Empirical habitat suitability models based on environmental conditions can augment surveillance gaps to describe the estimated potential spe...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
The magnitude and duration of vertebrate viremia is a critical determinant of arbovirus transmission, geographic spread, and disease severity. We find that multiple alphaviruses, including chikungunya (CHIKV), Ross River (RRV), and o'nyong 'nyong (ONNV) viruses, are cleared from the circulation of mice by liver Kupffer cells, impeding viral dissemination. Clearance from the circulation was independent of natural antibodies or complement factor C3, and instead relied on scavenger receptor SR-A6 (MARCO). Remarkably, lysine to arginine substitutions at distinct residues within the E2 glycoproteins of CHIKV and ONNV (E2 K200R)...
Source: eLife - Category: Biomedical Science Tags: Microbiology and Infectious Disease Source Type: research
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