Cryotherapy May Curb Taxane-Induced Dermatologic Side Effects Cryotherapy May Curb Taxane-Induced Dermatologic Side Effects
Cooling the scalp may help prevent taxane-induced alopecia, whereas frozen gloves and socks may prevent nail and cutaneous side effects of the drugs, researchers say.Reuters Health Information
Publication date: Available online 2 October 2018Source: Research in Veterinary ScienceAuthor(s): Lauren Proctor-Brown, Rebecca Hicks, Sarah Colmer, Danielle Guilfoyle, Barbara Dallap-Schaer, Amy L. Johnson, Joy TomlinsonAbstractDigital cryotherapy (DC) is frequently used as laminitis prophylaxis for horses. While DC with ice-water slurries is reported to be safe for up to 48 h, the safety of sleeve-style digital cryotherapy (SSDC) with ice in direct contact with the distal limb has not been evaluated. Our objective was to determine the incidence of distal limb pathologic conditions (DLPC) among horses treated with SSDC....
This study presents a novel, thermoelectric cryotherapy cap that aims to provide effective and controlled scalp cooling to prevent hair loss for chemotherapy patients. The cap's design consists of multiple thermoelectric coolers (TECs) evenly spaced and bonded to a soft thermal interface material, tightly fitted to a patient's head. A numerical model is developed to assess the performance of alternative cap designs in relation to their ability to achieve hair follicle hypothermia. Under ideal conditions, 26.5 W of heat removal from the scalp is required to achieve the clinically-significant follicle temperature target of...
Condition: Alopecia Areata Interventions: Procedure: Cryotherapy; Drug: Triamcinolone acetonide injection Sponsor: Assiut University Not yet recruiting
Conclusion: Superficial cryotherapy is an efficacious treatment modality with advantages of simplicity and noninvasiveness. It can be considered as a meaningful therapeutic modality for AA, especially when the disease status is limited to minimal to mild, or the conventional AA treatment is not applicable. PMID: 29200760 [PubMed]
This article presents an overview of the evidence for this strategy, as well as its impact on nursing care provision. PMID: 28738048 [PubMed - in process]
ConclusionsSuperficial cryotherapy is associated with minimal to no adverse events and exhibits high compliance and relatively good efficacy. Thus, this treatment is an important additional option for patients with AA of the eyebrow.