Rwanda:Rwandan Activist to Be Feted On World Thrombosis Day

[New Times] Christine Ashimwe, the founder of Rwanda Clot Awareness Network, has received a prestigious award for thrombosis advocacy achievements by the International Society on Thrombosis and Haemotasis (ISTH).
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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CONCLUSIONS: Intracoronary administration of tenecteplase did not reduce infarct size compared to abciximab in STEMI patients undergoing PPCI. Tenecteplase exhibited poorer myocardial reperfusion and might be associated with increased subacute stent thrombosis. PMID: 30418157 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
CONCLUSIONS: PPVI with the S3 valve appears feasible and safe in a wide range of patients with congenital heart defects, with good short-term haemodynamic and functional outcomes. PMID: 30418156 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
A PREVIOUSLY healthy 52-yr-old man was admitted to the intensive care unit for septic shock and diffuse alveolar hemorrhage caused by leptospirosis. He received high-dose norepinephrine (2.2 μg · kg−1· min−1); the heart rate was 155 beats/min, and the electrocardiogram revealed regular tachycardia with narrow QRS complexes (imageA,white arrows). A P wave (imageA, black arrows) was observed in the middle of each RR interval, and it was unclear if the rhythm was sinus tachycardia, atrial tachycardia, or atrial flutter. Transesophageal echocardiography, performed for evaluation of shock, included ...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
ConclusionsIn older adults treated with direct-acting oral anticoagulants after ischemic stroke, outcome rates varied considerably by drug and dosage.
Source: Drugs and Aging - Category: Geriatrics Source Type: research
Conclusions: The novel sensorized HVP has great potential to give early warning of possible subclinical valve thrombosis altering the valve leaflet motion, and to help in tailoring the anticoagulation therapy.
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
DiscussionThere has been no comparison of coupled and hand-sewn venous anastomoses using a robust and validated methodology preceded by a protocol and performing meta-analysis. Included studies are expected to be mainly observational and prone to bias; however, there is value in summarising the evidence, assessing its risk of bias and performing meta-analysis to guide clinicians. By using a broad approach including all types of flaps, we foresee inherent differences regarding the unit of analysis and different anatomic sites. This will limit the validity of our conclusions but is unavoidable. We will seek unpublished data ...
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Authors: Undas A, Zabczyk M Abstract Fibrin constitutes a major protein component of intravascular thrombi in all locations. Fibrin formation and its functions are essential for physiological hemostasis and the pathologic thrombosis. Formation of dense fibrin networks which are relatively resistant to lysis is observed in patients with venous or arterial thromboembolism, including myocardial infarction, ischemic stroke and venous thromboembolism. Measures of clot characteristics, in particular clot permeability and clot lysis time, may predict arterial and venous recurrent thromboembolic events. Medications, includ...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Authors: Miklosz J, Kalaska B, Mogielnicki A Abstract Predicting the clinical consequences of anticoagulant therapy by identifying gene variants could help in the risk assessment of thrombosis or bleeding before and after surgery and may result in choosing more beneficial therapy. This work provides an overview of pharmacogenetic data of commonly used anticoagulant medication. The review focuses on polymorphisms influencing the efficacy and safety of the parenteral and oral anticoagulants. There is evidence that heparin resistance and heparin-induced thrombocytopenia could be genetically determined but it does not ...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Conclusion: Patients with pancreatic cancer undergoing palliative chemotherapy have an increased risk of aTE. A predictive model showed that patients presented with 3 or 4 predictors had the highest risk for developing aTE.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
AbstractPurpose of the reviewTo review the management of women with mechanical heart valves during pregnancy, from preconception counseling through delivery with a summary of the latest guidelines.Recent findingsThe hypercoagulability of pregnancy combined with the imperfect choices of anticoagulant agents contribute to a high risk of complications in pregnant women with mechanical heart valves. Valve thrombosis remains a major concern, much of which occurs during the first trimester transition to heparin-based products. The safest method of anticoagulation, with the best balance of maternal and fetal risk, is use of low-d...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
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