Rwanda:Rwandan Activist to Be Feted On World Thrombosis Day

[New Times] Christine Ashimwe, the founder of Rwanda Clot Awareness Network, has received a prestigious award for thrombosis advocacy achievements by the International Society on Thrombosis and Haemotasis (ISTH).
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Conclusions: Our method of treatment presents a new approach for management of one of the most complicated orthopedic problems ever. Our method is economic, and cost and time saving, consuming less time and materials needed for the operation.
Source: Techniques in Orthopaedics - Category: Orthopaedics Tags: Novel Research Methods and Models Source Type: research
Background: Recombinant activated factor VII (rFVIIa) has been used off-label to treat or prevent severe bleeding in patients for whom conventional treatments are unsuccessful. However, studies in children remain limited. Procedure: To examine the efficacy and safety of rFVIIa, we performed a retrospective analysis of rFVIIa off-label use in a pediatric hematology/oncology cohort at a single center from 2006 to 2014. Results: Of 58 patients identified, 46 (79.3%) received rFVIIa to treat bleeding and 12 (20.7%) to prevent bleeding. Thirty-three (71.7%) patients had life-threatening bleeding. In the treatment group,...
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Original Articles Source Type: research
We report a case of MSI in a 12-year-old boy with homozygous sickle cell anemia (Hb SS) whose chronic transfusion therapy resulted in hypersplenism. The occurrence of a complicated MSI in our patient should perhaps further encourage elective splenectomy in such patients, despite known potential perioperative complications and postsplenectomy risks of infection and thrombosis.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Original Articles Source Type: research
AbstractWarfarin is dependent on multiple hepatic enzymes for metabolism while apixaban is a substrate for P-glycoprotein (P-gp) transport and hepatic CYP3A4 metabolism. The aim of this analysis was to assess the impact of interacting medication use on the treatment effects of apixaban versus warfarin. Outcomes were compared between apixaban and warfarin using Cox proportional hazards modeling according to the use of interacting medications at randomization in ARISTOTLE (n  = 18,201). Interacting medications for apixaban were identified as combined P-gp and 3A4 inhibitors or inducers while interacting medicat...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Transgender hormone therapy is associated with an increased risk for MI, stroke, and venous thromboembolism, underscoring the importance of patient counseling and close monitoring in this population.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news
Authors: Lecouffe-Desprets M, Graveleau J, Artifoni M, Connault J, Agard C, Pottier P, Hamidou M, Néel A Abstract Many factors can contribute to the risk of venous thrombosis observed in hemolytic diseases. Some mechanisms are related to hemolysis by itself, while others seem more specific to each disease. Despite recent advances in the quantification of this risk and in understanding its physiopathology, the association of hemolysis with venous thrombosis is often unknown. The purpose of this general review is to clarify the main pro-thrombotic mechanisms during hemolysis and to synthesize the clinical data...
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Condition:   Aortic Stenosis Intervention:   Sponsors:   Hospital San Carlos, Madrid;   FUNDACION PARA LA INVESTIGACION HOSPITAL CLINICO SAN CARLOS;   Instituto Carlos III Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Campo F, Fusconi M, Ciotti M, Diso D, Greco A, Cattaneo CG, de Vincentiis M Abstract Lemierre's syndrome is a rare and fatal disease and is also known as the forgotten disease to describe the rarity of this syndrome in the antibiotic era. However, in the last 20 years, the incidence of this disease has been increasing. Authors report a case of Lemierre's syndrome with extensive venous thrombosis involving right internal jugular veins with extension to the sigmoid and lateral sinus and also review the literature on the use of anticoagulant therapy in Lemierre's syndrome. A computerized Medline study was car...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
(N Engl J Med. 2018;379:1689–1691) Recent reports in the lay media have discussed increasing maternal mortality in the United States. In fact, women in the United States are more likely to die from childbirth-related or pregnancy-related causes than women in other high-income countries, with black women dying at a rate 3 to 4 times that of white women. Furthermore, the Centers for Disease Control and Prevention have identified 3 types of preventable complications: postpartum hemorrhage, severe hypertension, and venous thromboembolism. In this perspective article, the authors discussed 4 actions by which the health c...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
(Reg Anesth Pain Med. 2018;43:263–309) The American Society of Regional Anesthesia and Pain Medicine (ASRA) convened its Fourth Consensus Conference on Regional Anesthesia and Anticoagulation in conjunction with the European Society of Anesthesiology (ESA) in response to emerging patient safety issues. Among these are the heightened risk of neuraxial bleeding due to increasingly potent antithrombotic medications, changing standards for venous thromboembolism (VTE) prevention, and conflicting recommendations by various bodies and societies. Spinal hematoma is an uncommon and catastrophic complication of epidural or s...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mechanisms, Equipment, Hazards Source Type: research
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