Eczema Drug Dupilumab Spurs Hair Regrowth in Alopecia Totalis Eczema Drug Dupilumab Spurs Hair Regrowth in Alopecia Totalis
Shared immune characteristics of alopecia totalis and atopic dermatitis might explain the hair regrowth in a patient with alopecia totalis being treated with dupilumab for persistent eczema.Medscape Medical News
Condition: Alopecia Areata Intervention: Device: Tattoo machine (SOL Nova Device) Sponsor: Yale University Not yet recruiting
Abstract Mast cells are tissue-resident immune cells that are involved in inflammation and fibrosis but also serve beneficial roles, including tissue maintenance, angiogenesis, pathogen clearance, and immunoregulation. Their multifaceted response and the ability of their mediators to target multiple organs and tissues means that mast cells play important roles in numerous conditions, including asthma, atopic dermatitis, drug sensitivities, ischemic heart disease, Alzheimer disease, arthritis, irritable bowel syndrome, infections (parasites, bacteria and viruses), and cancer. As a result, mast cells have become an ...
Conclusions: While newer treatments like LLLT may be more efficacious than more traditional therapies like 5% minoxidil, the efficacy of the more recent treatment modalities needs to be further validated by future RCTs. PMID: 32250713 [PubMed - as supplied by publisher]
DISCUSSION: Diphencyprone reduced the level of Th1, Th17 and Th9 cytokines and increased the level of Th2 cytokines (IL-4) in the present study, which induced remission and promoted hair regrowth. PMID: 32249656 [PubMed - as supplied by publisher]
Conclusions: V20Gy and V40Gy were the strongest predictors for acute and chronic G2 hair-loss, respectively. The low-dose bath typical of VMAT corresponds to large areas of acute but transient alopecia. However, the steep dose gradient of VMAT allows to reduce the areas of the scalp that receive higher doses, minimizing the risk of permanent alopecia.The application of our dosimetric findings for the scalp may help in reducing the alopecia risk and also in estimating the probability of hair-loss during patient counseling before starting radiotherapy.
AbstractPatient-reported outcome (PRO) measures play an important role in clinical care. Currently, a broad-spectrum, validated PRO measure suitable for all dermatology patients, as part of clinical care, does not exist. Patient-reported Outcome Measures Information System (PROMIS) measures track specific domain outcomes across all diseases. To assess the relevance and utility of a computer-adaptive health assessment consisting of three PROMIS domains in routine dermatologic care. This retrospective study evaluated a PROMIS health assessment, consisting of three computer-adaptive test domains (pain interference, anxiety, a...
HAIR loss can be attributed to a wide range of causes and establishing the type of hair loss you have offers your best bet of finding a suitable treatment. If you experience a type of hair loss called alopecia areata, an oil derived from a popular herb has been shown to help.
If you’re like most people trying to do their part in the midst of the COVID-19 outbreak, you’re washing your hands diligently with soap and water many times a day. Excellent hand hygiene is one essential public health measure to help stop the spread of the novel coronavirus. Unfortunately, additional handwashing can result in dry skin and hand dermatitis, a rash that can manifest as red, itchy, cracked, or sore skin. People who have a history of eczema or who are prone to dry skin may be even more likely to develop dry, chapped hands during this pandemic. What’s happening to your hands? Intact skin acts ...
(North Carolina State University) A commonly expressed protein in skin -- periostin -- can directly activate itch-associated neurons in the skin, according to new research. Blocking periostin receptors on these neurons reduced the itch response in a mouse model of atopic dermatitis, or eczema.
A dermatologist answers some of your top COVID-19 concerns: what to do about dry hands, how to tackle skin damage from wearing PPE, and why we should expect stress-induced hair loss when the pandemic subsides.