ISPAD Position Statement on Type 1 Diabetes in Schools
Pediatric Diabetes,Volume 19, Issue 7, Page 1338-1341, November 2018.
It has been long known that the metabolic derangements of diabetes mellitus (both type 1 and type 2) could have important effects on the central nervous system, as assessed by many cognitive measures. This has been demonstrated in adults, as well as in children.
Publication date: Available online 22 July 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Oana P Zaharia, Klaus Strassburger, Alexander Strom, Gidon J Bönhof, Yanislava Karusheva, Sofia Antoniou, Kálmán Bódis, Daniel F Markgraf, Volker Burkart, Karsten Müssig, Jong-Hee Hwang, Olof Asplund, Leif Groop, Emma Ahlqvist, Jochen Seissler, Peter Nawroth, Stefan Kopf, Sebastian M Schmid, Michael Stumvoll, Andreas F H PfeifferSummaryBackgroundCluster analyses have proposed different diabetes phenotypes using age, BMI, glycaemia, homoeostasis model estimates, and islet autoantibodies. We ...
A Texas man with type 1 diabetes shares his story of overcoming hopelessness and founding a group for diabetics competing in Tough Mudder events.
Conditions: Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 1 Interventions: Drug: 3 hours humulin R 100 IU/mL PIT; Drug: 2 hours humulin R 100 IU/mL PIT Sponsors: Sciema UG; Innovative Diabetes Treatment Studies LLC. Not yet recruiting
Condition: Type1diabetes Interventions: Drug: Regular insulin (Humulin-R), intranasal route; Device: SipNose intranasal device Sponsors: HealthPartners Institute; International Diabetes Center at Park Nicollet; Juvenile Diabetes Research Foundation Not yet recruiting
Congenital malformations and perinatal mortality rates remain severalfold higher in pregnant women with type 1 diabetes than in the background population, and still only a minority of women plan their pregnancy. Optimizing glycemic control is the accepted goal, but remains challenging, and must be constantly balanced against the risks of hypoglycemia. Recent advances including Continuous Glucose Monitoring Systems, Continuous Subcutaneous Insulin Infusion, Closed Loop Devices and very Fast Acting Insulin Aspart analogs offer new possibilities to increase glucose time in target in selected, motivated patients, however their...
Conclusions 147 hospitalizations due to iatrogenic hypoglycemia were identified with an estimated global cost of € 407,441. Optimizing therapy with low-risk hypoglycemic medicines, improving access to continuous glucose monitoring systems and offering adequate education, could help address the causes of hypoglycemia.
The CEO of Diasome Pharmaceuticals shares his personal type 1 diabetes story, and how their product directs insulin to the right path for best absorption.
To investigate in a large population the proportion of daily basal insulin dose (BD) to daily total insulin dose (TD) (BD/TD) and its association with glycated hemoglobin A1c (HbA1c), body mass index (BMI)- SDS, and treatment modality in children with type 1 diabetes.
Authors: Udler MS, McCarthy MI, Florez JC, Mahajan A Abstract Over the last decade, there have been substantial advances in the identification and characterization of DNA sequence variants associated with individual predisposition to type 1 and type 2 diabetes. As well as providing insights into the molecular, cellular and physiological mechanisms involved in disease pathogenesis, these risk variants, when combined into a polygenic score, capture information on individual patterns of disease predisposition that have the potential to influence clinical management. In this review, we describe the various opportunitie...