Time, Flow, and Location Key to Lytic Sufficiency for Stroke

(MedPage Today) -- Recanalization factors pinned down in prospective analysis
Source: MedPage Today Radiology - Category: Radiology Source Type: news

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Publication date: Available online 20 September 2018Source: Revista Portuguesa de Cardiologia (English Edition)Author(s): Liliana Reis, Luís Paiva, Marco Costa, Joana Silva, Rogério Teixeira, Ana Botelho, Paulo Dinis, Marta Madeira, Joana Ribeiro, José Nascimento, Lino GonçalvesAbstractIntroductionPercutaneous closure of the left atrial appendage (LAA) is a promising therapy in patients with atrial fibrillation with high risk for stroke and contraindication for oral anticoagulation (OAC). Intracardiac echocardiography (ICE) may make this percutaneous procedure feasible in patients in whom transe...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
This ESH update was deemed necessary with the publication of new results of sham-controlled randomized blinded prospective trials with renal denervation (RDN). Proof of concept studies and first randomized trials (some were sham-controlled) displayed discrepant results about the efficacy of RDN. Three sham-controlled randomized trials of the 2.0 generation yielded now similarity in the average blood pressure decrease following RDN. Reduction of ambulatory blood pressure was approximately 5 to 7 mmHg and of office blood pressure 10 mmHg. Such a decrease in blood pressure by pharmacologic therapy has been found to be associa...
Source: Journal of Hypertension - Category: Cardiology Tags: Esh Statement Source Type: research
Objective: We aimed to investigate the relationship of BMI and waist circumference with the development of chronic kidney disease (CKD). Methods: A total of 12 672 hypertensive patients with estimated glomerular filtration rate (eGFR) at least 60 ml/min per 1.73 m2 from the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT) were included. The primary outcome was the development of CKD, defined as a decrease in eGFR of at least 30% and to a level of less than 60 ml/min per 1.73 m2 at the exit visit, or end-stage renal disease. A secondary outcome was rapid renal function decline, defined as ...
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Obesity Source Type: research
STROKE is a serious condition where the blood supply to the brain is cut off. It can have potential fatal consequences, but to prevent one happening experts recommend eating a healthy, balanced diet. A new study recommends following a particular diet, but it may be more effective for women rather than men.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 19 September 2018Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Laura N. Zamproni, Marco A.V.M. Grinet, Mayara T.V.V. Mundim, Marcella B.C. Reis, Layla T. Galindo, Fernanda R. Marciano, Anderson O. Lobo, Marimelia PorcionattoAbstractStem cell transplantation is a promising strategy to treat brain injuries. However, cell-based therapies are limited because poor local cell engraftment. Here, we present a polylactic acid (PLA) scaffold to support mesenchymal stem cells (MSCs) delivery in stroke. We isolated bone marrow MSCs from adult C57/Bl6 mice, cultured them on PLA ...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Conclusion: This work suggests that integrated LSI and Vis-OCT is a promising tool for investigating ischemic stroke in mouse models. Significance: For the first time, LSI and Vis-OCT are integrated to investigate ischemic strokes in rodent models.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
We describe our technique for totally thoracoscopic LAA exclusion with an epicardial clip device. This approach provides a safe and likely more effective alternative to LAA management than other endocardial devices.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsOpen repair of ATBAD with distal aortic arch involvement using the frozen elephant trunk procedure with LSCA-LCCA transposition obtained satisfactory outcomes. Avoidance of complications using hybrid repair, good postoperative recovery, and a low prevalence of late reintervention were achieved. The satisfactory results favored this technique for this lesion in this hybrid repair era.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsRadical resection and in situ reconstruction with CPA avoids placing prosthetic material in an infected field and provides good early and midterm outcomes. However, early postoperative imaging is necessary given the risk of pseudoaneurysm formation.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This study evaluated outcomes in younger patients, specifically aged 50 years and younger, after mechanical aortic valve replacement (mAVR) and bioprosthetic AVR (bAVR).MethodsFrom 1994 to 2016, 643 patients underwent AVR (411 mAVR and 232 bAVR) at age 50 or younger. Concomitant coronary artery bypass grafting and mitral valve procedures were also included. Propensity score-matching methods resulted in 170 evenly matched patient pairs. Primary end points were operative mortality and long-term survival. Secondary end points were stroke, major bleeding, and redo AVR. Median observation time was 8.1 years (range, 0 to 23.6 ye...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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