Gastroesophageal reflux disease and morbid obesity: evaluation and treatment

AbstractGastroesophageal reflux disease (GERD) is markedly increased among the obese population being recognized as one of the many obesity-related comorbidities. This concept should raise awareness, making physicians investigate more profoundly about this disease in this kind of patients. Currently, bariatric surgery is considered the gold standard treatment for morbid obesity. However, not all the operations are appropriate for the treatment of GERD and not all the patients are willing to receive bariatric surgery for the treatment of GERD. Even though sleeve gastrectomy has emerged as a suitable treatment option for morbid obesity, it has been related to development of de novo GERD or worsening the pre-existing one. Conversely, results after Roux-en-Y gastric bypass have been encouraging in this aspect, and it seems to be the best option for patients who suffer both diseases. Therefore, the presence of GERD should not be ignored at the time of deciding which type of surgery will be offered to the patient.
Source: Updates in Surgery - Category: Surgery Source Type: research

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ConclusionsRYGB is an effective therapy for patients with BE and reflux after SG. Its outcomes in the current study were BE remission in the majority of cases as well as a decrease in reflux activity. Further studies with larger cohorts are necessary to confirm these findings.
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionOAGB is more effective for %EWL and dyslipidemia remission than SG. In addition, OAGB may lower the risk of postoperative leak, gastroesophageal reflux disease, revision, and mortality. Further comparisons of the clinical outcomes of OAGB versus SG for morbid obesity would benefit from more high-quality controlled studies.
Source: Obesity Surgery - Category: Surgery Source Type: research
AbstractIntroductionSleeve gastrectomy (SG) has overtaken Roux-En-Y gastric bypass (RYGB) as the most common bariatric procedure worldwide. However, there is little long-term data comparing the two procedures.ObjectivesWe perform a systematic review and meta-analysis comparing 5-year outcomes of randomised controlled trials (RCTs) comparing RYGB and SG.MethodsMedline, Embase, The Cochrane Library, and NHS Evidence were searched for English language RCTs comparing RYGB with SG and assessed weight loss and/or comorbidity resolution at 5 years.ResultsFive studies were included in the final analysis. Meta-analysis demonstrates...
Source: Obesity Surgery - Category: Surgery Source Type: research
AbstractThe purpose of this study was to investigate the relationship between bariatric surgery (laparoscopic sleeve gastrectomy [LSG] and laparoscopic Roux-en-Y gastric bypass [LRYGB]) and gastroesophageal reflux disease (GERD). The number of obese patients with newly onset, worsened, or improved GERD after bariatric surgery in each article were extracted. In the pooled analysis, LSG was associated with a higher risk of GERD than LRYGB (odds ratio [OR] = 5.10, 95% confidence interval [CI] 3.60 –7.23,p
Source: Obesity Surgery - Category: Surgery Source Type: research
AbstractIntroductionBariatric surgery is increasingly performed. Since there are numerous surgical techniques, the effects of these on the esophageal function are still poorly understood. We aimed at assessing the effect of different techniques on esophagogastric junction (EGJ), esophageal peristalsis and reflux exposure using high-resolution manometry (HRM), and impedance-pH monitoring (MII-pH).MethodsAll obese patients underwent symptomatic questionnaires, endoscopy, HRM, and MII-pH before and 1  year after surgery. Esophageal function and EGJ were classified according to Chicago Classification V. 3.0. Intragastric ...
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
ConclusionEE is more prevalent after SG compared with RYGB in a pre-bariatric surgery cohort with GERD. SG is associated with significant esophageal physiologic changes conducive to GERD and its clinical consequences.
Source: Obesity Surgery - Category: Surgery Source Type: research
Gastroesophageal reflux can improve or worsen after bariatric surgery depending on procedure type. Our goal was to compare patient reported symptoms of reflux after gastric bypass (GB) and sleeve gastrectomy (SG) based on preoperative symptom severity.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Laparoscopic sleeve gastrectomy (LSG) is a commonly performed bariatric procedure in obesity management. Gastroesophageal reflux disease (GERD) in this population has reported rates of 23-100% GERD after LSG . GERD after LSG has been noted with recent studies demonstrating de novo reflux or symptom exacerbation despite weight loss. Fundoplication is not an option, and medically refractory GERD after LSG is usually treated with conversion to Roux-en-Y gastric bypass (RYGB). This video demonstrates the placement of a magnetic sphincter augmentation device after LSG as an alternative to conversion to RYGB.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Gastroesophageal reflux disease (GERD) is common in patients with obesity and different bariatric procedures have different effects on the symptoms. There is little long-term data regarding acid suppression therapy (AST: proton pump inhibitor or H2-blocker) use after bariatric surgery.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Abstract Obesity is a global health epidemic with considerable economic burden. Surgical solutions have become increasingly popular following technical advances leading to sustained efficacy and reduced risk. Sleeve gastrectomy accounts for almost half of all bariatric surgeries worldwide but concerns regarding its relationship with gastroesophageal reflux disease (GERD) has been a topic of debate. GERD, including erosive esophagitis, is highly prevalent in the obese population. The role of pre-operative endoscopy in bariatric surgery has been controversial. Two schools of thought exist on the matter, one that bel...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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