Nipah death toll rises to 16, but end of outbreak might be near

The death toll from the outbreak of Nipah virus has risen to 16 in the southern Indian state of Kerala.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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This article describes elements of design of such unit (e.g., space, infection control, waste disposal, safety of healthcare workers, partners to be involved in design and plan) which can be adapted to the context of either a new construction or makeshift construction on top of an existing structure. In view of a potential epidemic of COVID-19, specific requirements to handle it are also given. PMID: 32202258 [PubMed - as supplied by publisher]
Source: Indian J Med Res - Category: Research Authors: Tags: Indian J Med Res Source Type: research
As the world grapples with the COVID-19 pandemic, some experts say India — a country of more than 1.3 billion people — likely has many more cases than the conservative numbers currently being reported. The outbreak of the new coronavirus, which causes COVID-19, began in China and has since infected more than 124,000 people across more than 110 countries and territories around the world. More than 4,500 people worldwide have died after being infected with COVID-19. India has conducted nearly 5,000 COVID-19 tests so far, according to the World Health Organization, which says that the “country is responding ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Explainer Source Type: news
The northern side of Chatuchak Weekend Market feels a bit like Noah has hit hard times and decided to offload the entire contents of his Ark. In wooden cages, bright-plumed fighting cocks squawk and peck. Around the corner are snakes in plastic takeout containers, prices scrawled on them in sharpie. Hairless squirrel kits snooze in a pile as a meerkat and giant iguana gaze on. A pygmy monkey leaps about with a furious scowl, perhaps indignant at the 30,000 baht ($950) price tag fixed to his enclosure. Across the narrow alleyway, a lynx prowls restlessly within its cage. “He’s 250,000 baht [$7,900],” says ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 News Desk overnight Source Type: news
Conclusion: The rapid spread of infection uncovered the miserable state of health care system in implementing infection control measures. The case fatality and the socio-economic burden warrant developing appropriate treatments, vaccines and diagnostics.
Source: Journal of Global Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
[IPS] Colombo, Sri Lanka -In the wake of the latest coronavirus outbreak, movie buffs are drawing an eerie parallel with the film Contagion, a 2011 thriller based on a lethal airborne virus called Nipah and how the world's medical community battled to find a cure for the pandemic.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
They are considered the probable source of the coronavirus outbreak spreading from China. It turns out that they may have an immune system that lets them coexist with many disease-causing viruses.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Bats Viruses Epidemics Coronavirus (2019-nCoV) Marburg Virus Nipah Virus Hendra Virus SARS (Severe Acute Respiratory Syndrome) MERS (Middle East Respiratory Syndrome) Immune System Cell Host and Microbe (Journal) EcoHealth Alliance Source Type: news
Publication date: Available online 12 January 2020Source: Microbial PathogenesisAuthor(s): Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, Vladimir N. UverskyAbstractThe Nipah Virus (NiV) was first isolated during a 1998–9 outbreak in Malaysia. The outbreak initially infected farm pigs and then moved to humans from pigs with a case-fatality rate (CFR) of about 40%. After 2001, regular outbreaks occurred with higher CFRs (∼71%, 2001–5, ∼93%, 2008–12). The spread arose from drinking virus-laden palm date sap and human-to-human transmission. Intrinsic disorder analysis revealed strong correla...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
In this study, we tested ALS-8112 against NiV and other major human respiratory pneumo- and paramyxoviruses in 2 human lung epithelial cell lines, and demonstrated the ability of ALS-8112 to reduce infectious wild-type NiV yield by over 6 orders of magnitude with no apparent cytotoxicity. However, further cytotoxicity testing in primary cells and bone marrow progenitor cells indicated cytotoxicity at higher concentrations of ALS-8112. Our results warrant the evaluation of lumicitabine against NiV infection in relevant animal models.
Source: Antiviral Therapy - Category: Virology Source Type: research
In this study, we tested ALS-8112 against NiV and other major human respiratory pneumo- and paramyxoviruses in 2 human lung epithelial cell lines, and demonstrated the ability of ALS-8112 to reduce infectious wild-type NiV yield by over 6 orders of magnitude with no apparent cytotoxicity. However, further cytotoxicity testing in primary cells and bone marrow progenitor cells indicated cytotoxicity at higher concentrations of ALS-8112. Our results warrant the evaluation of lumicitabine against NiV infection in relevant animal models. PMID: 31935422 [PubMed - as supplied by publisher]
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
This week I attended the Nipah Virus International Conference in Singapore, marking the discovery of the virus 20 years ago. It’s an opportune time to recall the events around the emergence of this deadly pathogen. An outbreak of respiratory disease and encephalitis in pigs during 1998 took place in Ipoh City of Perak state in […]
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information encephalitis fruit bat Hendra virus henipavirus Nipah virus pandemic Pteropus respiratory disease spillover viral viruses Source Type: blogs
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