Grifols HyperRAB(R) (rabies immune globulin human) 300 IU/mL Receives FDA Approval to Treat Patients Exposed to Rabies Virus Infection

Innovative new formulation delivers higher concentration of anti-rabies virus antibodies per mL at wound site compared to other rabies immune globulin products on the market Reduced volume of medication offers potential for fewer injections for patients... Biopharmaceuticals, FDA Grifols, HyperRAB, rabies immune globulin, Rabies Virus
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news

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ira Fooks In South Africa, canid rabies virus (RABV) infection is maintained in domestic and wildlife species. The identification of rabies in African civets raised the question of whether this wildlife carnivore is a potential reservoir host of RABVs of direct and ancestral dog origin (dog-maintained and dog-derived origins) with an independent cycle of transmission. Genetic analyses of African civet nucleoprotein sequences for 23 African civet RABVs and historically published sequences demonstrated that RABVs from African civets have two origins related to dog and mongoose rabies enzootics. The data support observ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
 It’s often said that fear is the most dangerous virus on the planet. While a relatively small percentage of people will contract the new coronavirus, or COVID-19, the fear it provokes will chip away at the mental health of nearly everyone who hears about it. So why does COVID-19 inspire so much fear when there are other diseases lurking in the shadows? And what can we do about it? In today’s podcast, our guest Dr. David Batman, a registered medical practitioner in the U.K., discusses how this high level of unprecedented global panic is being intensified by the non-stop media, and specifically, social media....
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic General Health-related Interview Podcast The Psych Central Show Source Type: blogs
This study therefore defines the first stem cell-derived ex-vivo model system to study rabies pathogenesis in human neurons. This new model system demonstrates the potential for enabling an increased understanding of molecular mechanisms in human rabies, which could lead to improved control methods.
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
In this study we standardized anin vitro assay for determination of residual live virus combining viral isolation techniques with direct immunofluorescence detection and viral quantification by a molecular method. Standardization of viral recovery steps and quantification by RT-qPCR were performed and the combined method was shown to be 3 fold more sensitive than thein vivo assay. It was possible to identify viral suspensions cultures, which still had residual viable rabies virus particles, evidencing the importance to implement this method in quality control schemes of rabies vaccine production. In addition, this develope...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
by Susan Nadin-Davis, Tore Buchanan, Larissa Nituch, Christine Fehlner-Gardiner Despite proactive measures to prevent raccoon rabies entering Canada from the United States, several incursions of this disease have occurred. The largest outbreak, first reported in December 2015 in the city of Hamilton, Ontario, has resulted in the reporting of 449 animal cases as of December 31 , 2018. Initial phylogenetic studies on the index case suggested that this outbreak was not due to local cross-border spread from the Niagara region of the United States where raccoon rabies has persisted for several years. Phylogenetic analysis of w...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
A Utah man who became infected with rabies after handling several bats potentially exposed 279 other people, most of them health workers.
Source: JAMA - Category: General Medicine Source Type: research
BACKGROUND: Dog bite injury is one of the most common unintentional injuries affecting all age groups worldwide, both in developed and developing countries. Age, gender, and environmental exposure are among the most-cited risk factors. Dog bites and rabies...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Interdisciplinary approaches have been recommended to prevent epidemics (Rushton et al., 2018). The simultaneous consideration of bio-geo-demographic-temporal interactions in the design of epidemiologic policies could improve the bio-economic impact of such policies (Masiira et al., 2018). Furthermore, local geo-referenced and temporal data could unmask dynamic and complex relationships that influence disease dissemination (Rivas et al., 2010; Rivas et al., 2012). For instance, investigations of the biogeography associated with rabies could detect factors that promote epidemic spread as well as barriers that prevent dissem...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
The original version of the article unfortunately contained a typo error in second author name in the author group. The author name was incorrectly published as “Jesse Grewal” and the correct name is “Jessie Grewal”.
Source: EcoHealth - Category: Environmental Health Source Type: research
Abstract In Brazil, rabies occurs mainly within an urban cycle, in which dogs and bats are reservoirs. This paper aims to report the occurrence of rabies in Callithrix sp. in Niter ói, Rio de Janeiro, Brazil. In June 2019 a hybrid specimen was referred for diagnosis. The Direct Fluorescent Antibody, Mouse Inoculation, and Polymerase Chain Reaction tests were positive. A phylogenetic analysis was compatible with antigenic variant 3, characteristic of Desmodus rotundus. New stu dies should be undertaken to elucidate the real role of callitrichids in the urban rabies cycle.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
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