Catalytic Enantioselective Hetero-dimerization of Acrylates and 1,3-Dienes

JacsCatalytic Enantioselective Hetero-dimerization of Acrylates and 1,3-Dienes: 1,3-Dienes are ubiquitous and easily synthesized starting materials for organic synthesis, and alkyl acrylates are among the most abundant and cheapest feedstock carbon sources. A practical, highly enantioselective union of these two readily available precursors giving valuable, enantio-pure skipped 1,4-diene esters (with two configurationally defined double bonds) is reported. The process uses commercially available cobalt salts and chiral ligands.

Source: Organometallic Current - November 28, 2017 Category: Chemistry Tags: Co catalyzed Dimerization Source Type: blogs