Novan's interim CEO outlines future focus
Novan ’s (Nasdaq: NOVN) interim CEO Kelly Martin – who is also CEO of Novan shareholder Malin Life Sciences Holding – said on an investor call Wednesday morning that strengthening Novan’s balance sheet is the most important focus in the near-term. Cash has continued to be a primary concern for Mo rrisville-based Novan in recent months, and the company has been struggling to regain footing following mixed Phase 3 trial results for its acne product SB204 that sent its stock plummeting 75 percent. As…
Authors: Mansouri P, Azizian Z, Najafi Z, Hejazi S, Younespour S Abstract BACKGROUND: Oral Isotretinoin (13-cis-retinoic acid)is a gold standardtreatment for severe forms of acne with cheilitis as a most frequent complication.we designed this novel study to investigate the therapeutic effect of Trichloroacetic Acid(TCA) 33% as compared with placebo to treat cheilitis. METHODS: In this pilot study, 90 acne vulgaris patients between 18 to 50 years, who refered dermatologic clinic with cheilitis, were assigned to either case (TCA) or control (Vaseline) group using permuted-block randomization from 2013 to 2015,wit...
CONCLUSIONS: Fourteen prospective studies representing 671 participants were included in this review. Modalities investigated included face washing frequency, true soap/syndet cleansing bars, antiseptic cleansers, alpha and beta-hydroxy (i.e. salicylic) acid cleansers, and several proprietary formulations. Given the low number of well-performed clinical studies of cleansers and washing, it is difficult to formulate reliable recommendations. We hope that our findings highlight the necessity of further investigation in this area. PMID: 29460655 [PubMed - as supplied by publisher]
CONCLUSION: Once-daily dapsone gel, 7.5% was effective, safe, and well tolerated in patients with all skin phototypes who were treated for moderate acne. J Drugs Dermatol. 2018;17(2):160-167. PMID: 29462223 [PubMed - in process]
How effective are light-based interventions for acne vulgaris?The British Journal of Dermatology
A number of diseases are treated using light therapy. These include acne, actinic keratosis, jaundice, Paget’s disease, and psoriasis. Modern light blankets use arrays of LEDs to produce illumination, but light emitted by LEDs can be quite...
In the first year after a new diagnosis of acne, patients ’ risk for a diagnosis of major depressive disorder spikes by more than 60 percent compared to the general population, a new study shows.Reuters Health Information
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