HGP Counterfactuals, Part 4: Sequencing Tech Landscape Circa 1992

In thisseries leading to a pair of Human Genome Project alternative histories, I've been warming up with a trio of analyses of the technology landscape.  At first I couldn't decide on the order to post these in, but then it was clear to me: a progression of scale fromphysical maps of the genome tohow to organize the sequencing of the BACs, and now to the actual sequencing technologies which were in play.  In particular, how there was a very rapid evolution from 1992 (when I first was deeply exposed to this angle by attending Hilton Head) to 1997 (when I defended, but also the outcome was clear).  In this time period, a large number of possible options essentially compressed to a single one: automa ted fluorescent dideoxy sequencing.  That outcome was not clear in 1992Read more »

Source: Omics! Omics! - November 13, 2016 Category: Bioinformatics Authors: Keith Robison Source Type: blogs