Giant Retroperitoneal Liposarcoma: The Silent Tumour

Publication date: Available online 3 August 2016 Source:Cirugía Española (English Edition) Author(s): Jorge Galván Fernández, María Isabel Jiménez Cuenca, Susana González Fuentes, Fernanda Benavides de la Rosa
Source: Cirugia Espanola - Category: Surgery Source Type: research

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ConclusionPD during RPS resection is feasible, and it may be necessary to achieve complete resection. However, considering the complexity and risk, it should be performed by an experienced surgical team. The long-term survival benefit of this procedure should be verified by further large-scale multi-institutional studies.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Authors: Miyake M, Oda Y, Nishimura N, Morizawa Y, Ohnishi S, Hatakeyama K, Fujii T, Hori S, Gotoh D, Nakai Y, Anai S, Torimoto K, Tsukamoto S, Fujii H, Kido A, Honoki K, Matsumura Y, Okajima E, Tanaka N, Fujimoto K Abstract Evidence is limited regarding the immunologic profile and immune microenvironment of soft tissue sarcoma subtypes. The aim of the present study was to describe the clinical significance and prognostic implications of PD-L1, PD-L2, and PD-1 in patients with retroperitoneal sarcoma (RSar). In this retrospective, multicenter, collaborative study, medical charts were reviewed and the immunohistoche...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
AbstractPurposeWell-differentiated liposarcoma, the most common subtype of liposarcoma, should be discriminated from benign lipoma. However, features on sonography for discriminating these two types of tumor have not been fully investigated. The present study was therefore aimed at clarifying differences in sonographic findings between well-differentiated liposarcoma and lipoma.MethodsThe study population comprised 23 cases of well-differentiated liposarcoma and 181 cases of lipoma. We investigated differences in sonographic appearance and pathological findings between the two types of tumor.ResultsWell-differentiated lipo...
Source: Journal of Medical Ultrasonics - Category: Radiology Source Type: research
Conditions:   Liposarcoma;   CRC;   Prostate Cancer;   Breast Neoplasms;   Adenocarcinoma of Lung;   Solid Tumors Interventions:   Drug: PF-07220060;   Combination Product: Letrozole;   Combination Product: Fulvestrant Sponsor:   Pfizer Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractDedifferentiated liposarcoma (DDLPS) is one of the four subtypes of liposarcomas; it is characterized by the amplification of the 12q13-15 region, which includesMDM2 andCDK4 genes. DDLPS has an extremely high local recurrence rate and is refractory to chemotherapy and radiation, which leads to poor prognosis. Therefore, a novel therapeutic strategy should be urgently established for improving the prognosis of DDLPS. Although patient-derived cell lines are important tools for basic research, there are no DDLPS cell lines available from public cell banks. Here, we report the establishment of a novel DDLPS cell line. ...
Source: Human Cell - Category: Cytology Source Type: research
Extremity liposarcoma represents 25% of extremity soft tissue sarcoma and has a better prognosis than liposarcoma occurring in other anatomic sites. The purpose of this study was to develop two nomograms for p...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research
Myxoid liposarcoma (MLS) has the tendency to metastasize extrapulmonary. Although prognostic factors at the initial diagnosis of MLS have been reported, those at diagnosis of metastasis remain unclear. The pur...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research
Conclusions: Our study showed that the DLK1 gene induces tumorigenesis in various sarcomas and is associated with invasive mechanism in sarcoma. These results suggest DLK1 could serve as a possible therapeutic target in a variety of sarcomas. PMID: 32904069 [PubMed - in process]
Source: Clinics in Orthopedic Surgery - Category: Orthopaedics Tags: Clin Orthop Surg Source Type: research
Conclusion DFML is a rare special variant of lipoma. It is benign, and it seems to be misdiagnosed as myxoid liposarcoma prior to the admission to our hospital. The pathological histomorphology and immunohistochemistry phenotypes are helpful to the diagnosis and differential diagnosis. Given that DFML mainly occurs in the elderly, this case is rare and worthy to be reported since it occurs in children. Ziel Untersuchung der pathologischen Merkmale und der Differenzialdiagnose eines dendritischen Fibromyxolipoms (DFML) in der Pädiatrie. Methode Wir berichten über den Fa...
Source: Klinische Padiatrie - Category: Pediatrics Authors: Tags: Diagnostic and Treatment Recommendation Source Type: research
Journal of Gynecologic Surgery, Ahead of Print.
Source: Journal of Gynecologic Surgery - Category: OBGYN Authors: Source Type: research
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