Giant Retroperitoneal Liposarcoma: The Silent Tumour

Publication date: Available online 3 August 2016 Source:Cirugía Española (English Edition) Author(s): Jorge Galván Fernández, María Isabel Jiménez Cuenca, Susana González Fuentes, Fernanda Benavides de la Rosa
Source: Cirugia Espanola - Category: Surgery Source Type: research

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Publication date: Available online 17 August 2019Source: Urology Case ReportsAuthor(s): Mehdi Kardoust Parizi, Solmaz Ohadian Moghadam, Seyed Ali MomeniAbstractGenitourinary tract liposarcoma is considered as the second most commonly reported type of sarcomas. Renal liposarcoma with tumor invasion to inferior vena cava (IVC) is distinctly rare. This tumor has a relatively indolent clinical course with risk of local recurrences (20%-85% rate) after surgery. Angiomyolipomas (AML) are the most important differential diagnosis because both are large fat-containing lesions. Herein, a patient with upper pole kidney liposarcoma w...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
ConclusionSystematic BMRI in MRCLS patients following treatment frequently identify extra-pulmonary metastasis in asymptomatic patients within the first 5 years of follow-up. Despite a long survival can be expected after diagnosis, extra-skeletal metastasis was a signal of disseminated disease.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
British Journal of Cancer, Published online: 14 August 2019; doi:10.1038/s41416-019-0550-2Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
AbstractRetroperitoneal liposarcoma is usually asymptomatic until it is large enough to compress the surrounding organs. Here, we report a rare atypical case of primary retroperitoneal dedifferentiated liposarcoma who presented primarily with the misguiding and challenging paraneoplastic symptoms of high-grade fever and thrombocytosis instead of demonstrating the usual compressive symptoms. Such an extremely rare clinical presentation may mislead the diagnostic and treatment approach towards the search for medical causes, without a hint, that the tumor itself is causing these symptoms. Complete tumor excision usually leads...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Mediastinal lipoma/liposarcoma is a rare tumor of the mediastinum.
Source: Journal of Cardiothoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Case report Source Type: research
Conditions:   Synovial Sarcoma;   Myxoid Liposarcoma Intervention:   Genetic: ADP-A2M4 Sponsor:   Adaptimmune Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Discussion: Up to 45% of sarcoma patients experience some form of psychological distress at disease presentation. Patients desire information about their diagnosis and treatment. Tailored interventions to individual psychological comorbidity and improved patient education resources would be beneficial. PMID: 31354383 [PubMed]
Source: Sarcoma - Category: Cancer & Oncology Tags: Sarcoma Source Type: research
ConclusionHere we have reported a case of pulmonary metastasis from retroperitoneal liposarcoma following limited surgery. In cases where respiratory function is limited, lower lobe segmentectomy can be an effective treatment. For the treatment of a single pulmonary metastasis from retroperitoneal liposarcoma, metastasectomy was considered to be effective as long as no local recurrence was seen after initial primary tumor resection.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
CONCLUSIONS: Conventional urothelial and adjacent sarcomatoid morphologies of MIBC arise from the same common ancestor and share a basal-like phenotype. However, divergence between the morphologies at the genome, transcriptome, and proteome level suggests differential sensitivity to therapy. PMID: 31358384 [PubMed - as supplied by publisher]
Source: Urologic Oncology - Category: Urology & Nephrology Authors: Tags: Urol Oncol Source Type: research
We present a 62-year-old woman with an intraparenchymal mass involving the left frontoparietal lobes. Histologic examination demonstrated a mesenchymal neoplasm with a dense reticulin network and pleomorphic lipoblasts. Immunohistochemical stain for adipophilin highlighted intracytoplasmic vacuoles. MDM2 immunostain was negative. A diagnosis of pleomorphic liposarcoma was made. There was no evidence of an extracranial primary neoplasm by imaging or physical exam. Pleomorphic liposarcoma may rarely present as a solitary intracranial mass, an entity that must be entertained in the differential diagnosis of pleomorphic tumors...
Source: Clinical Neuropathology - Category: Pathology Authors: Tags: Clin Neuropathol Source Type: research
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