Neutrophil Infiltration and Function in the Pathogenesis of Inflammatory Airspace Disease

Neutrophils are an important cell type often considered the body's "first responder" in the response to inflammatory insult or damage. They are recruited to the tissue of the lungs during inflammatory airspace diseases and can perform unique and complex functions that range from helpful to harmful. Additionally, neutrophil function is unique in the lungs through heterogeneity of the inflammatory cascade and retention in the vasculature. They are known to "marginate" or remain stagnant in the lungs even during non-disease conditions.

Source: American Journal of Pathology - January 31, 2024 Category: Pathology Authors: Maureen E. Haynes, David P. Sullivan, William A. Muller Tags: Mini-Review Source Type: research