Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro

Conclusions
The possibility to distinguish patient cohorts with different capacity to respond to immune modulatory compounds in vitro by a simple analysis of the phenotypic CD8 T cell exhaustion profile deserves evaluation of its clinical applicability.

Source: Gut - October 6, 2023 Category: Gastroenterology Authors: Rossi, M., Vecchi, A., Tiezzi, C., Barili, V., Fisicaro, P., Penna, A., Montali, I., Daffis, S., Fletcher, S. P., Gaggar, A., Medley, J., Graupe, M., Lad, L., Loglio, A., Soffredini, R., Borghi, M., Pollicino, T., Musolino, C., Alfieri, A., Brillo, F., La Tags: Open access, Gut Hepatology Source Type: research