Diagnosis and Treatment of Refractory GERD

AbstractPurpose of ReviewRefractory GERD (rGERD) is a common condition with a significant and costly impact on patients and healthcare systems alike. As such, it is imperative to understand the tools available to diagnose and treat rGERD.Recent FindingsIn this review, the modalities used to diagnose rGERD are discussed in detail, including esophagogastroduodenoscopy (EGD) and ambulatory reflux monitoring (the “gold standard”). The adjunctive role of high-resolution esophageal manometry (HREM) is also addressed. A comprehensive discussion of the various treatment options is provided, including lifestyle modifications, pharmacotherapy, endoscopic therapies, and surgical options. Promising emerging ther apies are explored. Management of concomitant functional esophageal disorders is also discussed.SummaryWe review the current diagnostic and management algorithms for the management of rGERD and provide insight into emerging therapies.
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research