The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model

Arthrofibrosis is a common inflammatory complication of joint trauma and surgery. 5lipoxygenase (5-LO) is a key enzyme involved in inflammation. Inhibition of 5-LO has been shown to reduce inflammation in hear...

Source: Journal of Experimental Orthopaedics - June 21, 2023 Category: Orthopaedics Authors: Alexander D. Jeffs, Michael Boyd, Landon Larabee, Matthew Shelton, Alexander Bassil, Ross Taylor and David Berkoff Tags: Original Paper Source Type: research